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Computed Tomography for Lung Cancer

N/A
Waitlist Available
Led By Alain Tremblay, MD
Research Sponsored by University of Calgary
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5 years
Awards & highlights

Study Summary

This trial will test whether regular, low-dose CT scans can help detect and prevent lung cancer.

Eligible Conditions
  • Lung Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Comparison of screening enrollment criteria (Risk prediction model (RPM) vs. NLST criteria)
Randomized trial of smoking cessation intervention in screened individuals (smoking status [smoking rates assessed via questionnaire and abstinence confirmed by saliva nicotine or exhaled carbon minoxide])
Secondary outcome measures
Evaluation of nodule risk calculator
Health Economics Analysis (healthcare payer and all direct health-care related cost)

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Smoking cessation counselingExperimental Treatment1 Intervention
Active smokers randomized to this arm will be contacted by a trained smoking cessation counselor and offered cessation support and advice.
Group II: Screening armExperimental Treatment1 Intervention
Annual low dose screening chest CT scan x 3.
Group III: Smoking cessation controlActive Control1 Intervention
Active smokers randomized to this arm will receive general information on available smoking cessation resources.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Computed Tomography
2017
Completed Phase 2
~2720

Find a Location

Who is running the clinical trial?

University of CalgaryLead Sponsor
792 Previous Clinical Trials
868,354 Total Patients Enrolled
Alberta Cancer FoundationOTHER
17 Previous Clinical Trials
4,833 Total Patients Enrolled
Alain Tremblay, MDPrincipal InvestigatorUniversity of Calgary
1 Previous Clinical Trials
200 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Journal of Thoracic OncologyJournal
A Randomized Controlled Study of Integrated Smoking Cessation in a Lung Cancer Screening Program
Tremblay, Alain, Niloofar Taghizadeh, Jane Huang, Debra Kasowski, Paul MacEachern, Paul Burrowes, Andrew J. Graham, et al.. 2019. “A Randomized Controlled Study of Integrated Smoking Cessation in a Lung Cancer Screening Program”. Journal of Thoracic Oncology. Elsevier BV. doi:10.1016/j.jtho.2019.04.024.
JTO Clinical and Research ReportsJournal
Two-year Follow-up of a Randomized Controlled Study of Integrated Smoking Cessation in a Lung Cancer Screening Program
Tremblay, Alain, Niloofar Taghizadeh, Paul MacEachern, Paul Burrowes, Andrew J. Graham, Stephen C. Lam, Huiming Yang, et al.. 2021. “Two-year Follow-up of a Randomized Controlled Study of Integrated Smoking Cessation in a Lung Cancer Screening Program”. JTO Clinical and Research Reports. Elsevier BV. doi:10.1016/j.jtocrr.2020.100097.
clinicaltrials.govStudy
Alberta Lung Cancer Screening Program
Dr. Alain Tremblay 2015. "Alberta Lung Cancer Screening Program". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02431962.
~80 spots leftby Apr 2025
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