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Antioxidant

MitoQ for COPD

N/A
Recruiting
Led By Paula Rodriguez-Miguelez, PhD
Research Sponsored by Virginia Commonwealth University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Clinically diagnosed of COPD
Global Initiative for obstructive lung disease (GOLD) Stages II to IV
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 6 weeks
Awards & highlights

Study Summary

This trial tests if MitoQ, a mitochondrial-targeted antioxidant, can improve cardiovascular health in patients with COPD.

Who is the study for?
This trial is for adults with moderate to severe COPD (GOLD Stages II to IV). Participants must have a clinical diagnosis of COPD. They can't join if they have heart disease, are on vasoactive meds, have fluid in their lungs, gangrene, uncontrolled high blood pressure, Raynaud's Phenomenon, sleep apnea, a history of coagulation issues or diabetes.Check my eligibility
What is being tested?
The study tests whether MitoQ—a mitochondrial-targeted antioxidant—can improve cardiovascular health in people with COPD. It compares the effects of MitoQ against a placebo (a substance with no therapeutic effect) to see if there's any benefit.See study design
What are the potential side effects?
While specific side effects for MitoQ aren't listed here, antioxidants like it could potentially cause upset stomachs or allergic reactions. The exact side effects will be monitored and recorded throughout the trial.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have been diagnosed with COPD.
Select...
My lung condition is moderate to very severe.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and 6 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Skeletal Muscle Oxygenation
Body Weight Changes
Body Weight Changes
Secondary outcome measures
Change in arterial stiffness
Body Weight Changes

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: MitoQExperimental Treatment1 Intervention
Participants will take 1 pill each day for 6 weeks
Group II: PlaceboPlacebo Group1 Intervention
Participants will take 1 pill each day for 6 weeks
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
MitoQ
2006
Completed Phase 2
~230

Find a Location

Who is running the clinical trial?

Virginia Commonwealth UniversityLead Sponsor
698 Previous Clinical Trials
22,884,971 Total Patients Enrolled
American Heart AssociationOTHER
326 Previous Clinical Trials
4,933,806 Total Patients Enrolled
Paula Rodriguez-Miguelez, PhDPrincipal InvestigatorVirginia Commonwealth University

Media Library

MitoQ (Antioxidant) Clinical Trial Eligibility Overview. Trial Name: NCT05605548 — N/A
Chronic Obstructive Pulmonary Disease Research Study Groups: MitoQ, Placebo
Chronic Obstructive Pulmonary Disease Clinical Trial 2023: MitoQ Highlights & Side Effects. Trial Name: NCT05605548 — N/A
MitoQ (Antioxidant) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05605548 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any unfilled slots available for this trial?

"Information hosted on clinicaltrials.gov reveals that this particular trial is not presently recruiting participants, being initially posted on the 1st November 2022 and last amended 4 days later. However, there are currently 477 other trials actively looking for patients."

Answered by AI

Who else is applying?

What site did they apply to?
Virginia Commonwealth University
What portion of applicants met pre-screening criteria?
Did not meet criteria

Why did patients apply to this trial?

Looking to feel healthier.
PatientReceived no prior treatments
Recent research and studies
clinicaltrials.govStudy
Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD)
2023. "Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05605548.
All > Copd
~8 spots leftby Dec 2024
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