Low Dose CT for Lung Disease

Phase-Based Progress Estimates
Lung Disease+1 MoreLow Dose CT - DiagnosticTest
40 - 80
All Sexes
What conditions do you have?

Study Summary

This trial will compare CT scan findings of firefighters to a control group, and see if there is a relationship between work exposure and findings. They will also test a method to better identify high-risk patients.

Eligible Conditions
  • Lung Cancer
  • Lung Disease

Treatment Effectiveness

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: 12 months

12 months
Coronary artery calcification (CAC) ordinal scores
High-risk nodule detection rate
Interstitial lung disease detection rate
Nodule detection rate

Trial Safety

Trial Design

1 Treatment Group

Low-Dose CT
1 of 1

Experimental Treatment

850 Total Participants · 1 Treatment Group

Primary Treatment: Low Dose CT · No Placebo Group · N/A

Low-Dose CT
Experimental Group · 1 Intervention: Low Dose CT · Intervention Types: DiagnosticTest

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,703 Previous Clinical Trials
30,852,358 Total Patients Enrolled
Erica T Warner, ScDPrincipal InvestigatorMassachusetts General Hospital
Lecia V Sequist, MDPrincipal InvestigatorMassachusetts General Hospital

Eligibility Criteria

Age 40 - 80 · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are willing and able to receive CT screening at MGH or who have been screened via LDCT within the past year at MGH or another institution, and are willing to release their images to the study.
You are between 40 and 80 years of age.