Study Summary
This trial will compare CT scan findings of firefighters to a control group, and see if there is a relationship between work exposure and findings. They will also test a method to better identify high-risk patients.
Eligible Conditions
- Lung Cancer
- Lung Disease
Treatment Effectiveness
Effectiveness Progress
Study Objectives
2 Primary · 2 Secondary · Reporting Duration: 12 months
12 months
Coronary artery calcification (CAC) ordinal scores
High-risk nodule detection rate
Interstitial lung disease detection rate
Nodule detection rate
Trial Safety
Safety Progress
Trial Design
1 Treatment Group
Low-Dose CT
1 of 1
Experimental Treatment
850 Total Participants · 1 Treatment Group
Primary Treatment: Low Dose CT · No Placebo Group · N/A
Low-Dose CT
DiagnosticTest
Experimental Group · 1 Intervention: Low Dose CT · Intervention Types: DiagnosticTestTrial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months
Who is running the clinical trial?
Massachusetts General HospitalLead Sponsor
2,703 Previous Clinical Trials
30,852,358 Total Patients Enrolled
Erica T Warner, ScDPrincipal InvestigatorMassachusetts General Hospital
Lecia V Sequist, MDPrincipal InvestigatorMassachusetts General Hospital
Eligibility Criteria
Age 40 - 80 · All Participants · 4 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:You are willing and able to receive CT screening at MGH or who have been screened via LDCT within the past year at MGH or another institution, and are willing to release their images to the study.
You are between 40 and 80 years of age.
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Conditions
Cancer Related
Treatments