Home-Based Pulmonary Rehabilitation for Interstitial Lung Disease

JT
JH
BT
Overseen ByBenjamin Thomas
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Mayo Clinic
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if a home-based exercise program, known as home-based pulmonary rehabilitation, can help individuals with fibrotic interstitial lung diseases (f-ILD) breathe easier and become more active. The program includes health coaching and tele-monitoring to support participants in improving their quality of life. It suits those diagnosed with idiopathic pulmonary fibrosis or similar lung diseases who experience significant shortness of breath. As an unphased trial, this study offers participants the chance to contribute to innovative research that could enhance their daily lives.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this home-based pulmonary rehabilitation is safe for patients with fibrotic interstitial lung disease?

Research has shown that performing pulmonary rehabilitation exercises at home is generally safe for people with interstitial lung disease (ILD). In past studies, patients improved their exercise capacity and quality of life without major safety issues. Specifically, one study found that individuals who did these exercises at home experienced better long-term outcomes, such as easier breathing and increased physical activity, compared to those who did not.

The treatment includes exercises and health coaching performed at home, and most people manage it well. No reports of serious side effects from the rehabilitation itself have emerged. This suggests that the program is likely safe for most people with fibrotic interstitial lung diseases (f-ILD). Always consult a doctor before starting any new treatment.12345

Why are researchers excited about this trial?

Researchers are excited about home-based pulmonary rehabilitation for fibrotic interstitial lung disease because it offers a more flexible and accessible alternative to traditional hospital or clinic-based rehab programs. Unlike standard treatments that often require frequent hospital visits, this approach allows patients to perform exercises and improve their lung health from the comfort of their own homes. This can lead to increased adherence to the rehabilitation program and potentially better outcomes, as patients can integrate physical activity more seamlessly into their daily routines. Additionally, by reducing the need for travel, it may be particularly beneficial for those who live far from healthcare facilities or have mobility issues.

What evidence suggests that this home-based pulmonary rehabilitation is effective for fibrotic interstitial lung disease?

Research has shown that pulmonary rehabilitation exercises at home can improve the quality of life for people with fibrotic interstitial lung diseases (f-ILD). In this trial, participants will engage in a home-rehab program designed to increase physical activity in daily life. Studies have found that patients in these programs experience better breathing and increased physical activity. This rehabilitation involves exercises and health coaching provided remotely, ensuring easy and convenient access. Long-term studies suggest that these programs help people continue to improve their daily activities over time. Overall, evidence supports home-based pulmonary rehab as a helpful treatment option for managing f-ILD symptoms.23456

Who Is on the Research Team?

TM

Teng Moua, MD

Principal Investigator

Mayo Clinic

Are You a Good Fit for This Trial?

This trial is for people with a type of lung scarring called fibrotic Interstitial Lung Diseases who feel significantly short of breath. They must have at least 10% lung fibrosis visible on CT scans and be able to understand the study's instructions. It's not for those who've recently done pulmonary rehab, are in hospice care, currently experiencing a flare-up of symptoms, or can't walk due to other health issues.

Inclusion Criteria

I often feel short of breath doing daily activities.
I have been diagnosed with a lung scarring disease with more than 10% fibrosis.

Exclusion Criteria

I completed my physical rehabilitation within the last 3 months.
My condition is worsening right now.
I can understand and follow instructions.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in a home-based pulmonary rehabilitation program with health coaching and tele-monitoring, including gentle upper body exercises, walking, and breathing practice for 12 weeks.

12 weeks
Weekly check-in calls (telephone)

Follow-up

Participants are monitored for safety and effectiveness after treatment, with assessments of respiratory-related quality of life and physical activity.

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Home-based pulmonary rehabilitation
Trial Overview The study tests if doing pulmonary rehabilitation at home with health coaching and monitoring through technology can improve how patients with lung scarring diseases feel about their breathing and increase their physical activity.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Home-based pulmonary rehab for fibrotic interstitial lung diseaseExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials
3,427
Recruited
3,221,000+

Boehringer Ingelheim

Industry Sponsor

Trials
2,566
Recruited
16,150,000+

Citations

Comparing the Effectiveness of Home-Based Pulmonary ...This study compares the effectiveness of a home-based, technology-delivered pulmonary rehabilitation (PR) program with health coaching in ...
Home-based Pulmonary Rehabilitation and Health ...Pulmonary rehabilitation is an intervention shown to improve patient-reported quality of life (QoL) in fibrotic interstitial lung disease patients (f-ILD).
Effect of a home-based pulmonary rehabilitation program ...The aims of this study are to evaluate the efficacy of home-based PR on functional capacity and health-related quality of life in people with ILD.
Study Details | NCT06751069 | Home-based Pulmonary ...The purpose of this clinical trial is to determine the impact of a home-based pulmonary rehabilitation program with health coaching on patient-reported ...
Remote pulmonary rehabilitation for interstitial lung diseaseLong-term evaluation of home-based pulmonary rehabilitation in patients with fibrotic idiopathic interstitial pneumonias. ERJ Open Res 2019 ...
Pulmonary rehabilitation for interstitial lung disease - PMCPulmonary rehabilitation in people with ILD has beneficial effects on exercise capacity, symptoms, quality of life and survival compared with no pulmonary ...
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