Tissue Collection for Stomach Cancer

Overseen By Hedy Kindler, MD

Age: Any Age

Sex: Any

Trial Phase: Academic

Sponsor: University of Chicago

Disqualifiers: None

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

1000 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to collect and store tissue and blood samples from patients with various types of gastrointestinal cancers, such as stomach, esophageal, pancreatic, and liver cancer. The goal is to create a database to help researchers better understand these cancers and develop future treatments. Patients diagnosed with one of these cancers who require surgery or a diagnostic procedure, such as a biopsy, might be suitable candidates for this trial. As an unphased study, this trial offers participants the opportunity to contribute to groundbreaking research that could lead to new cancer treatments.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that these procedures are safe?

Research has shown that biopsy procedures are usually safe and well-tolerated. Most problems, such as bleeding or infection, are minor and occur soon after the procedure. Serious issues are rare.

Surgery, although common, carries more risks, including bleeding, infection, or organ damage. However, safety checklists can greatly reduce these risks.

Both biopsy and surgery have been widely used and studied, so their safety is well understood. Participants can feel confident that these procedures are routine and generally safe. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to gather vital tissue samples from patients with various cancers, including gastric, esophageal, and colorectal cancers, during surgery or biopsy. This approach is unique because it allows scientists to study the molecular and genetic characteristics of these cancers in detail. By analyzing these tissue samples, researchers hope to uncover new insights into cancer behavior and identify potential targets for future treatments, ultimately leading to more personalized and effective therapies. This trial represents a crucial step in advancing our understanding of cancer and improving patient outcomes.

Who Is on the Research Team?

Daniel Catenacci, MD

Principal Investigator

University of Chicago

Are You a Good Fit for This Trial?

Inclusion Criteria

any patient diagnosed with Gastric (stomach) Cancer, Esophageal (foodpipe) Cancer, Pancreas Cancer, Liver Cancer, Biliary (gallbladder) Cancer, Gastrointestinal Stromal Tumor, Peritoneal Mesothelioma (cancer in the lining of the abdomen), Neuroendocrine (of or relating to the cells that release a hormone into the blood in response to a neural stimulus) Tumor, Anal Cancer or Colorectal Cancer cancer that requires you to undergo a surgical or diagnostic procedure

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Tissue and Blood Collection

Collection and storage of normal and malignant tissue and blood samples from patients with various cancers

1 year

Database Creation

Creation of a database for the collected tissue and blood samples, allowing access to relevant clinical information

1 year

Follow-up

Participants are monitored for safety and effectiveness after sample collection

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Biopsy
• Surgery

Who Is Running the Clinical Trial?

University of Chicago

Lead Sponsor

Trials

1,086

Recruited

844,000+

Citations

1.

radiologyinfo.org

radiologyinfo.org/en/info/biopgen

General Biopsy

Generally, a biopsy procedure is safe and causes minimal injury. Complications that may result from biopsies include: Bleeding; Infection; Accidental injury ...

2.

mayoclinic.org

mayoclinic.org/tests-procedures/needle-biopsy/about/pac-20394749

Needle biopsy

You may not be able to return to work or drive right after your procedure if your needle biopsy is done with sedation or general anesthesia.

3.

pmc.ncbi.nlm.nih.gov

pmc.ncbi.nlm.nih.gov/articles/PMC12564087/

Navigating Biopsy Safety: Complication Rates Under ...

Most complications were mild (85.7%) with no life-threatening events. The majority of complications occurred within four hours post-biopsy (93.9 ...

4.

betterhealth.vic.gov.au

betterhealth.vic.gov.au/health/conditionsandtreatments/biopsy

Biopsy

Complications from a biopsy · Excessive bleeding (haemorrhage) · Infection · Puncture damage to nearby tissue or organs · Skin numbness around the biopsy site.

5.

my.clevelandclinic.org

my.clevelandclinic.org/health/diagnostics/15458-biopsy-overview

What Is a Biopsy? Purpose & Results

Biopsy complications are rare, but they can happen. Depending on the biopsy procedure, complications may include: Excessive bleeding. Infection. Scarring. You ...