← Back to Search

Procedure

Living Donor Liver Transplantation for Liver Metastases

N/A

Waitlist Available

Led By David K Al-Adra, MD, PhD

Research Sponsored by University of Wisconsin, Madison

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Study Summary

This trial will test if it is safe and effective to get a liver transplant from a living donor after chemotherapy for people with colorectal cancer that has spread to the liver and cannot be removed surgically.

Eligible Conditions

Liver Metastasis from Colon Cancer

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Overall Survival (OS)

Secondary outcome measures

Disease Free Survival (DFS)

Number of Sites of Recurrence per Participant

Quality of Life Survey Score: EORTC QLQ-C30

+3 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Intent to Treat: LDLTExperimental Treatment1 Intervention

Living Donor Liver Transplantation

Group II: Control GroupActive Control1 Intervention

Enrolled but does not receive LDLT

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Wisconsin, MadisonLead Sponsor

1,182 Previous Clinical Trials

3,167,387 Total Patients Enrolled

David K Al-Adra, MD, PhDPrincipal InvestigatorUniversity of Wisconsin, Madison

David P Al-Adra, MD, PhDPrincipal InvestigatorUniversity of Wisconsin, Madison

Media Library

Living Donor Liver Transplantation (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT05175092 — N/A

Liver Metastasis Research Study Groups: Intent to Treat: LDLT, Control Group

Liver Metastasis Clinical Trial 2023: Living Donor Liver Transplantation Highlights & Side Effects. Trial Name: NCT05175092 — N/A

Living Donor Liver Transplantation (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05175092 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible to participate in this research endeavor?

"This clinical trial will accept 50 volunteers aged 18 to 65 who are diagnosed with liver neoplasms. To qualify, they must meet the Recipient Inclusion Criteria and be willing to provide informed consent, reside in America, have a negative pregnancy test for women of childbearing age, ECOG score 0 or 1 at all times prior to LDLT , biopsy-verified colorectal LM that meets specific characteristics, non-resectable LM (determined by consultation between three HPB specialists), synchronous or metachronous disease which is discussed during multidisciplinary tumor rounds."

Answered by AI

What is the current number of participants in this clinical exploration?

"Affirmative. Details on clinicaltrials.gov reveal that this medical experiment is actively recruiting, with the initial post having been made on December 1st 2022 and last updated October 24th 2022. The study necessitates 50 participants from a single trial site."

Answered by AI

Is eligibility for this trial restricted to individuals under sixty years of age?

"This clinical trial is only available to those over the age of consent and under 65. For patients younger than 18, there are 47 corresponding studies offered; for seniors aged 65 or above, 757 applicable trials exist."

Answered by AI

Is this research endeavour currently recruiting participants?

"As per data available on clinicaltrials.gov, this experiment is currently recruiting participants. The trial was initially advertised on December 1st 2022 and has been updated as recently as October 24th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Living Donor Liver Transplantation for CRC Liver Metastases

2023. "Living Donor Liver Transplantation for CRC Liver Metastases". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05175092.