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Michigan Alcohol Improvement Network-Alcohol Reduction and Treatment tool for Liver Disease (MAIN-ART Trial)

N/A
Waitlist Available
Led By Jessica Mellinger, MD, MSc
Research Sponsored by University of Michigan
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 6 months
Awards & highlights

MAIN-ART Trial Summary

This trial is testing if giving patients with liver disease from alcohol different, personalized treatment options will increase their engagement and reduce alcohol use.

Eligible Conditions
  • Liver Disease
  • Alcohol Use Disorder

MAIN-ART Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Acceptability of the MAIN-ART Tool as Measured by Post-intervention Surveys
Feasibility of MAIN-ART Tool as Measured by Recruitment Rates
Feasibility of MAIN-ART Tool as Measured by Retention Rates
Secondary outcome measures
Alcohol Treatment Engagement as Measured by Number of Participants Who Engaged in Any Alcohol Cessation or Reduction Visit as Measured by Self-report.
Alcohol Use Frequency as Measured by the Alcohol Timeline Follow-back (TLFB) Interview

MAIN-ART Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: MAIN-ART Behavior ToolExperimental Treatment1 Intervention
The Michigan Alcohol Improvement Network- Alcohol Reduction and Treatment Tool (MAIN-ART) behavioral intervention is an online web application with two modules: misconception correction and tailored, preference-sensitive alcohol use disorder (AUD) treatment matching.
Group II: Routine careActive Control1 Intervention
Patients randomized to usual care will receive a pamphlet for alcohol treatment referral to the University of Michigan Addiction Treatment Services, but will receive no further education from the research team.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Michigan Alcohol Improvement Network-Alcohol Reduction and Treatment tool
2020
N/A
~60

Find a Location

Who is running the clinical trial?

University of MichiganLead Sponsor
1,797 Previous Clinical Trials
6,377,998 Total Patients Enrolled
National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH
801 Previous Clinical Trials
1,365,225 Total Patients Enrolled
Jessica Mellinger, MD, MScPrincipal Investigator - University of Michigan
University of Michigan C.S. Mott Children's Hospital, University of Michigan Health System, Von Voigtlander Women's Hospital
Northwestern University Medical Sch (Medical School)
1 Previous Clinical Trials
268 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Michigan Alcohol Improvement Network- Alcohol Reduction and Treatment Trial
Jessica Mellinger 2020. "Michigan Alcohol Improvement Network- Alcohol Reduction and Treatment Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04473482.
~13 spots leftby Apr 2025
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