← Back to Search

Adults with or without HIV infection for Alcohol Consumption

N/A

Waitlist Available

Led By Robert Cook

Research Sponsored by University of Florida

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 1 year

Awards & highlights

Study Summary

This trial will study the effects of reducing alcohol consumption for 30 days on behavioral and health functions, and how these changes last for up to 90 days. The study will also identify barriers and facilitators related to drinking reduction.

Eligible Conditions

Alcohol Consumption
Liver Disease
Human Immunodeficiency Virus Infection
Neurocognitive Disorder
Chronic Inflammation

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Neurocognitive Functions

Secondary outcome measures

Change in Brain Function

Change in Drinks/week in the Past 30 Days

Change in Neuroinflammation

+3 more

Side effects data

From 2021 Phase 2 trial • 118 Patients • NCT02896712

10%

Drowsiness

10%

Weakness

10%

Muscle Aches

10%

Blurry Vision

10%

Fatigue

Symptoms of Congestive Heart Failure

Skin Rash

Difficulty Walking

Asthma Attack

Upper Respiratory Infection

Vomiting

Increased Urination

100%

80%

60%

40%

20%

Study treatment Arm

Phase 2: DC Plus CM, With Modafinil

Phase 2: ACT Plus CM, With Modafinil

Phase 2: DC Plus CM Only

Phase 2: DC Plus CM, With Placebo

Phase 1: Acceptance and Commitment Therapy (ACT) Plus Contingency Management (CM) Only

Phase 1: Drug Counseling (DC) Plus Contingency Management (CM) Only

Phase 2: ACT Plus CM Only

Phase 2: ACT Plus CM, With Placebo

Trial Design

1Treatment groups

Experimental Treatment

Group I: Adults with or without HIV infectionExperimental Treatment1 Intervention

Participants will be asked to stop drinking for at least 30 and up to 90 days. The study will use Contingency Management (CM) with financial incentives to encourage participants to maximally reduce alcohol consumption.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Contingency Management (CM)

2016

Completed Phase 2

~420

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Brown UniversityOTHER

456 Previous Clinical Trials

562,901 Total Patients Enrolled

National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH

799 Previous Clinical Trials

1,362,331 Total Patients Enrolled

University of FloridaLead Sponsor

1,340 Previous Clinical Trials

715,516 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this medical experiment open to participants who are 70 or older?

"This particular clinical trial is exclusive to patients aged 50-75. By contrast, there are 388 trials for minors and 2052 studies available for elderly individuals."

Answered by AI

Are there any openings for enrollment in this investigation?

"According to clinicaltrials.gov, this trial is not presently enlisting patients as the last update was in September of 2022. However, there are 2570 other studies actively seeking volunteers at present."

Answered by AI

What characteristics are necessary for someone to qualify as a participant in this trial?

"Eligibility for the clinical trial is limited to those between 50 and 75 who are active alcohol drinkers. The research team intends to enrol 180 individuals in total."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

30-to-90 Day Challenge: Effects of Alcohol Cessation on Health Outcomes

2017. "30-to-90 Day Challenge: Effects of Alcohol Cessation on Health Outcomes". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03353701.