← Back to Search

Procedure

TLI for Paroxysmal Nocturnal Hemoglobinuria (Mini-allo Trial)

N/A
Waitlist Available
Led By Jeffrey W. Andrey, M.D.
Research Sponsored by Scripps Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one year
Awards & highlights

Mini-allo Trial Summary

This trial is testing whether a less intense form of chemotherapy can be used before a stem cell transplant to treat different types of blood cancer.

Eligible Conditions
  • Paroxysmal Nocturnal Hemoglobinuria
  • Aplastic Anemia
  • Melanoma
  • Acute Lymphoblastic Leukemia
  • Hodgkin's Lymphoma
  • Myelodysplastic Syndrome
  • Chronic Lymphocytic Leukemia
  • Kidney Cancer
  • Non-Hodgkin's Lymphoma
  • Mantle Cell Lymphoma
  • Breast Cancer
  • Ovarian Cancer
  • Multiple Myeloma
  • Acute Myeloid Leukemia
  • Sarcoma
  • Leukemia
  • Thymoma
  • Waldenstrom Macroglobulinemia

Mini-allo Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one year
This trial's timeline: 3 weeks for screening, Varies for treatment, and one year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Engraftment
Secondary outcome measures
Graft-versus-host disease

Mini-allo Trial Design

2Treatment groups
Experimental Treatment
Group I: TLIExperimental Treatment1 Intervention
Total lymphoid irradiation conditioning
Group II: Cladribine + melphalanExperimental Treatment1 Intervention
Cladribine + melphalan conditioning
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Nonmyeloablative Allogeneic Transplant
2001
N/A
~40

Find a Location

Who is running the clinical trial?

Scripps HealthLead Sponsor
54 Previous Clinical Trials
11,630 Total Patients Enrolled
Jeffrey W. Andrey, M.D.Principal InvestigatorScripps Health

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Nonmyeloablative Allogeneic Transplant
Jeffrey Andrey, MD 2001. "Nonmyeloablative Allogeneic Transplant". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01272817.
~2 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top