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Stem Cell Transplant

Donor Stem Cell Transplant for Leukemia and Kidney Cancer

N/A
Waitlist Available
Led By Charles A. Linker, MD
Research Sponsored by University of California, San Francisco
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Matched unrelated donor available with specific HLA matching criteria
Diagnosis of metastatic renal cell carcinoma
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is studying how well a donor stem cell transplant works in treating patients with hematologic cancer, metastatic kidney cancer, or aplastic anemia.

Who is the study for?
This trial is for patients with certain blood cancers, advanced kidney cancer, or aplastic anemia unresponsive to standard treatments. Participants must have a closely matched stem cell donor and cannot be pregnant or nursing. They should not have severe liver, heart, kidney issues, very low lung function, uncontrollable infections or extremely rapid cancer progression.Check my eligibility
What is being tested?
The study tests if low-dose chemotherapy followed by a transplant of donor stem cells can stop cancer growth and prevent immune rejection. It also examines the effects of additional donor T cells infusion and medications like antithymocyte globulin, cyclosporine, and mycophenolate mofetil in preventing immune responses against normal cells.See study design
What are the potential side effects?
Possible side effects include reactions to the transplant leading to graft-versus-host disease (immune cells attacking the body), infection risks due to weakened immunity from chemotherapy and immunosuppressive drugs used after transplantation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have a donor who matches the specific HLA criteria.
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I have been diagnosed with kidney cancer that has spread.
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I have been diagnosed with a specific blood cancer like leukemia or lymphoma.
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My aplastic anemia did not improve with immune system treatments.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

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Who is running the clinical trial?

University of California, San FranciscoLead Sponsor
2,500 Previous Clinical Trials
15,236,436 Total Patients Enrolled
6 Trials studying Myeloproliferative Disorders
182 Patients Enrolled for Myeloproliferative Disorders
National Cancer Institute (NCI)NIH
13,654 Previous Clinical Trials
40,933,118 Total Patients Enrolled
257 Trials studying Myeloproliferative Disorders
77,782 Patients Enrolled for Myeloproliferative Disorders
Charles A. Linker, MDPrincipal InvestigatorUniversity of California, San Francisco
2 Previous Clinical Trials
452 Total Patients Enrolled
1 Trials studying Myeloproliferative Disorders
25 Patients Enrolled for Myeloproliferative Disorders

Media Library

Donor Stem Cell Transplant (Stem Cell Transplant) Clinical Trial Eligibility Overview. Trial Name: NCT00295997 — N/A
Myeloproliferative Disorders Research Study Groups:
Myeloproliferative Disorders Clinical Trial 2023: Donor Stem Cell Transplant Highlights & Side Effects. Trial Name: NCT00295997 — N/A
Donor Stem Cell Transplant (Stem Cell Transplant) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00295997 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this experiment presently admitting participants?

"Evidence suggests this medical study is not currently seeking volunteers. In light of the fact that it was first uploaded on May 1st 2005, and most recently altered on January 3rd 2014, there are no open slots for participants at this time. Nevertheless, a plethora of other trials—7364 to be exact—are actively recruiting right now."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, or Aplastic Anemia
2005. "Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, or Aplastic Anemia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00295997.
All > Aplastic Anemia > Polycythemia Vera
~2 spots leftby Apr 2025
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