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Lidocaine patch for Postoperative Pain (LPACS Trial)

Phase 3
Waitlist Available
Led By Audrey Merriam, MD, MS
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up the first 72 hours post-operative, up to 4 days
Awards & highlights

LPACS Trial Summary

This trial looks at whether or not using lidocaine patches immediately after a c-section can help with pain control and decrease the amount of opioids needed.

Eligible Conditions
  • Postoperative Pain
  • Opioid Use Disorder
  • Obstetric Pain

LPACS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~the first 72 hours post-operative, up to 4 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and the first 72 hours post-operative, up to 4 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Narcotic Use
Secondary outcome measures
Pain

LPACS Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Lidocaine Patch GroupExperimental Treatment1 Intervention
This group will be women who were randomized to receive a lidocaine patch for postoperative pain following cesarean delivery in addition to routine postoperative pain management.
Group II: Control GroupActive Control1 Intervention
This group will be women randomized to routine postoperative pain management following cesarean delivery.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Lidocaine patch
2021
Completed Phase 3
~350

Find a Location

Who is running the clinical trial?

Yale UniversityLead Sponsor
1,852 Previous Clinical Trials
2,738,348 Total Patients Enrolled
1 Trials studying Postoperative Pain
160 Patients Enrolled for Postoperative Pain
Audrey Merriam, MD, MSPrincipal InvestigatorAssistant Professor; Assistant Professor, Department of Obstetrics, Gynecology and Reproductive Sciences
1 Previous Clinical Trials
80 Total Patients Enrolled
Christopher Arkfeld, MDPrincipal InvestigatorYale University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any openings to partake in this research project?

"As per the information on clinicaltrials.gov, recruitment for this trial has ceased since it was last amended on November 9th 2022. Despite this study having concluded its recruitment phase, there are currently 405 alternative trials that are still accepting participants."

Answered by AI

Are there any other experiments that have been executed utilizing the Lidocaine patch?

"At the moment, there are 118 ongoing clinical trials for lidocaine patch. Of those 118 live studies, 31 have reached phase 3. The majority of these experiments take place in Calgary, Alberta yet 1094 sites across the globe are currently running research into this medication."

Answered by AI

What potential perils should one be aware of when using a Lidocaine patch?

"Lidocaine patch has already been through multiple stages of data analysis, so the safety rating is 3. This indicates there are well-documented evidence that this intervention both works and safe to use."

Answered by AI

Who are the eligible subjects for this medical investigation?

"This trial requires 100 female participants who have given birth through either cesarean section or another form of delivery and are currently suffering from postoperative pain. The age range for eligible candidates lies between 18 and 52 years old."

Answered by AI

How many participants have enrolled in this research endeavor thus far?

"This clinical trial is no longer active. It was first posted on October 10th 2021 and last modified on November 9th 2022. If you are exploring other studies, 287 trials with a focus on postoperative pain and 118 pertaining to the lidocaine patch are currently recruiting participants."

Answered by AI

What ailments is the Lidocaine patch typically employed to address?

"The lidocaine patch is a popular treatment for cervical syndrome, as well as other maladies such as minor burns, transplantation, and osteoporosis."

Answered by AI

Is the enrollment criteria for this study restricted to those over forty years of age?

"This clinical trial's inclusion parameters necessitate that participants fall between 18 and 52 years of age. For those under the legal age or above 65, there are 48 trials for the former group and 322 for seniors respectively."

Answered by AI
~27 spots leftby Apr 2025