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Embolization Agent

Embozene Microspheres for Chronic Knee Pain

N/A

Waitlist Available

Led By Yan Epelboym, MD, MPH

Research Sponsored by Brigham and Women's Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

Study Summary

This trial is testing a new pain treatment for people who have had knee surgery. It will measure how well the treatment works at reducing pain six months after the treatment.

Eligible Conditions

Chronic Knee Pain
Knee Pain Swelling
Arterial Blockage

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

KOOS - Pain subscale KOOS Scale - Pain

Secondary outcome measures

Analgesic Utilization

CRP & IL-6

KOOS - Non-Pain Components

+2 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Genicular artery embolizationExperimental Treatment1 Intervention

Study participants will undergo genicular artery embolization (GAE) for treatment of chronic moderate to severe pain following knee arthroplasty or revision arthroplasty. Embolization will be performed using Embozene Microspheres.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Embozene Microspheres

2014

N/A

~300

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Brigham and Women's HospitalLead Sponsor

1,614 Previous Clinical Trials

11,470,835 Total Patients Enrolled

GuerbetIndustry Sponsor

68 Previous Clinical Trials

93,722 Total Patients Enrolled

Yan Epelboym, MD, MPHPrincipal InvestigatorBrigham and Women's Hospital

1 Previous Clinical Trials

41 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this experiment open to elderly participants aged 75 and above?

"Patients who meet the criteria for this trial must be between 40 and 80 years old. Additionally, there are two separate trials open to people below 18 and 34 more clinical opportunities available to those over 65."

Answered by AI

Who qualifies as an eligible participant in this clinical experiment?

"This research is seeking 10 individuals between 40 and 80 years old with painful knees that have not responded to pharmacological or intra-articular injections. Additionally, they must be ambulatory, possess no history of total or revision arthroplasty in the symptomatic knee, report moderate to severe pain (as indicated by a VAS score ≥50mm), demonstrate an absence of pregnancy as determined via urine HCG testing, consent to the study's protocol through signing a form and have the mental capacity required for angiography, ultrasound imaging and MRI tests."

Answered by AI

Are there available slots for volunteers to join this experiment?

"Data on clinicaltrials.gov indicates that this investigation is no longer enrolling participants, having been initially posted on July 1st 2022 and most recently updated February 10th 2022. However, 35 other trials are actively searching for patients at the moment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty Pain

Yan Epelboym, M.D.,M.P.H. 2022. "Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty Pain". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05248308.