Blood Flow Restriction Therapy for Anterior Cruciate Ligament (ACL) Injury

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Anterior Cruciate Ligament (ACL) Injury+1 MoreBlood Flow Restriction Therapy - Other
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

This trial found that BFR may improve ACL graft maturation compared to physical therapy alone.

Eligible Conditions
  • Anterior Cruciate Ligament (ACL) Injury
  • Knee Injuries

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

3 Primary · 4 Secondary · Reporting Duration: 2 weeks, 3 months, 6 months

Month 6
Difference in MRI imaging of Graft
International Knee Documentation Committee (IKDC)
Isokinetic Dynamometer
Single Assessment Numerical Evaluation (SANE)
Visual Analog Scale (VAS)
3 months, 6 months
Difference in Quadriceps Volume & Cross-sectional Area
Difference in Thigh Circumference Measurement

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Physical Therapy without BFR
1 of 2
Physical Therapy with BFR
1 of 2

Active Control

Experimental Treatment

40 Total Participants · 2 Treatment Groups

Primary Treatment: Blood Flow Restriction Therapy · No Placebo Group · N/A

Physical Therapy with BFR
Other
Experimental Group · 1 Intervention: Blood Flow Restriction Therapy · Intervention Types: Other
Physical Therapy without BFR
Other
ActiveComparator Group · 1 Intervention: Standard Postoperative Physical Therapy · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 2 weeks, 3 months, 6 months

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,165 Previous Clinical Trials
35,768,508 Total Patients Enrolled
Seth Sherman, MDPrincipal InvestigatorStanford University
1 Previous Clinical Trials
40 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are aged 18 or older.