Study Summary
This trial found that BFR may improve ACL graft maturation compared to physical therapy alone.
Eligible Conditions
- Anterior Cruciate Ligament (ACL) Injury
- Knee Injuries
Treatment Effectiveness
Effectiveness Progress
Study Objectives
3 Primary · 4 Secondary · Reporting Duration: 2 weeks, 3 months, 6 months
Month 6
Difference in MRI imaging of Graft
International Knee Documentation Committee (IKDC)
Isokinetic Dynamometer
Single Assessment Numerical Evaluation (SANE)
Visual Analog Scale (VAS)
3 months, 6 months
Difference in Quadriceps Volume & Cross-sectional Area
Difference in Thigh Circumference Measurement
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Physical Therapy without BFR
1 of 2
Physical Therapy with BFR
1 of 2
Active Control
Experimental Treatment
40 Total Participants · 2 Treatment Groups
Primary Treatment: Blood Flow Restriction Therapy · No Placebo Group · N/A
Physical Therapy with BFR
Other
Experimental Group · 1 Intervention: Blood Flow Restriction Therapy · Intervention Types: OtherPhysical Therapy without BFR
Other
ActiveComparator Group · 1 Intervention: Standard Postoperative Physical Therapy · Intervention Types: OtherTrial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 2 weeks, 3 months, 6 months
Who is running the clinical trial?
Stanford UniversityLead Sponsor
2,165 Previous Clinical Trials
35,768,508 Total Patients Enrolled
Seth Sherman, MDPrincipal InvestigatorStanford University
1 Previous Clinical Trials
40 Total Patients Enrolled
Eligibility Criteria
Age 18+ · All Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:You are aged 18 or older.
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Conditions
Cancer Related
Treatments