Nanochon Chondrograft for Meniscus Tear
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new implant called the Nanochon Chondrograft to determine its safety for individuals with knee cartilage damage. The goal is to assess the implant's effectiveness in knee surgeries. Individuals who have had an MRI showing knee issues in the last six months and can communicate in English may qualify for this study. As an unphased trial, this study provides a unique opportunity to contribute to groundbreaking research in knee surgery solutions.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are on steroid treatment or prescription narcotic medication. It's best to discuss your specific medications with the trial team.
What prior data suggests that the Nanochon Chondrograft is safe for treating cartilage lesions in the knee?
Research shows that the Nanochon Chondrograft, a new implant for repairing knee cartilage, has delivered promising results in early tests. Trials on large animals demonstrated that the implant successfully helped regrow damaged cartilage.
Although this marks the first human testing of the implant, Health Canada has approved it for human trials. This approval doesn't guarantee safety but indicates that the implant has passed initial safety checks for testing in people.
As this is an early stage of testing, information about its safety in humans remains limited. However, Health Canada's approval suggests that the treatment is considered safe enough for further study in people.12345Why are researchers excited about this trial?
Unlike the standard treatments for meniscus tears, which often involve physical therapy, anti-inflammatory medications, or surgical repair, the Nanochon Chondrograft is unique because it uses a bioengineered scaffold for cartilage regeneration. This experimental treatment is implanted either through mini arthrotomy or arthroscopic surgery, offering a potentially less invasive option compared to traditional open surgery. Researchers are excited because this innovative use of nanotechnology could promote faster healing and better integration with existing tissues, potentially improving joint function and reducing recovery time.
What evidence suggests that the Nanochon Chondrograft is effective for cartilage lesions in the knee?
Research shows that the Nanochon Chondrograft is designed to help knee cartilage heal. This 3D-printed implant allows immediate weight-bearing and movement, crucial for recovery. Studies in large animals have shown promising results for cartilage regrowth. The implant aims to rebuild cartilage and bone, essential for knee function. Although research on humans is ongoing, the technology behind the Chondrograft shows potential for effectively treating knee cartilage damage.13678
Are You a Good Fit for This Trial?
This trial is for English-speaking men and women aged 22 to 60 with a knee cartilage lesion, who can consent to the study. They must have had an MRI of the knee within the last six months.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo mini arthrotomy or arthroscopic surgical implantation of the Nanochon Chondrograft
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Nanochon Chondrograft
Trial Overview
The Nanochon Chondrograft Implant is being tested as a primary surgical treatment for knee cartilage damage. This early feasibility study aims to assess its safety in humans for the first time.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Mini arthrotomy or arthroscopic surgical implantation of the Nanochon Chondrograft
Find a Clinic Near You
Who Is Running the Clinical Trial?
Nanochon, Inc.
Lead Sponsor
Citations
1.
lifesciencemarketresearch.com
lifesciencemarketresearch.com/insights/the-memo-nanochon-creating-a-new-clinical-standard-for-cartilage-restorationNanochon Creating a New Clinical Standard for Cartilage ...
Nanochon's preclinical studies—including large-animal models—have demonstrated remarkable success in cartilage regeneration. Early data from the latest study ...
2.
engineering.gwu.edu
engineering.gwu.edu/holmes-nanochon-approved-human-trial-3d-printed-knee-implantHolmes' Nanochon Approved for Human Trial of 3D-Printed ...
Here is an excerpt from the article: “Chondrograft is a 3D printed, minimally invasive implant developed to support knee cartilage regeneration.
3.
businessofbiofabrication.com
businessofbiofabrication.com/2025/07/13/nanochon-receives-green-light-from-health-canada-for-first-in-human-trial-of-3d-printed-chondrograft-implant/Nanochon Receives Green Light from Health Canada for First ...
Chondrograft™ is a 3D printed, minimally-invasive cartilage implant that uniquely enables immediate weight-bearing and joint motion a key ...
4.
businesswire.com
businesswire.com/news/home/20250716081016/en/Nanochon-Announces-Health-Canada-Approval-for-First-in-Human-InvestigationNanochon Announces Health Canada Approval for First in ...
The study is designed to assess the safety and performance of Chondrograft™, and procedural goals include regrowth of the cartilage-bone matrix, ...
ORTHOFLASH® | Orthopedic Company Updates
... Results include outcomes for 200+ shoulders and show ... meniscal implant indicated for use in the reinforcement and repair of soft tissue injuries.
6.
cultivate-md.com
cultivate-md.com/nanochon-announces-health-canada-approval-for-first-in-human-investigation/Nanochon Announces Health Canada Approval for First in ...
The study is designed to assess the safety and performance of Chondrograft™, and procedural goals include regrowth of the cartilage-bone ...
Our Technology
Chondrograft™ is designed to fit securely into the damaged area of the knee using a simple press-fit procedure.
Collagen-Based Interventions for Meniscal Tears
Oral supplementation provided rapid symptomatic relief within one to three months with significant improvements in pain (Visual Analog Score ( ...
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