Motivational interviewing for Kidney Failure, Chronic

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Vanderbilt Dialysis Clinic, Nashville, TN
Kidney Failure, Chronic+1 More
Motivational interviewing - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This study is evaluating whether a set of motivational strategies can improve dialysis treatment adherence in African Americans.

See full description

Eligible Conditions

  • Kidney Failure, Chronic
  • End Stage Renal Disease on Dialysis

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Motivational interviewing will improve 1 primary outcome and 5 secondary outcomes in patients with Kidney Failure, Chronic. Measurement will happen over the course of Baseline, Week 6, Week 10.

Month 3
Dialysis treatment adherence
Week 10
Change in Apathy
Change in Autonomous Regulation
Change in Autonomy Support
Change in Optimism
Change in Perceived competence

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Standard of Care
1 of 2
Intervention
1 of 2
Active Control
Experimental Treatment

This trial requires 30 total participants across 2 different treatment groups

This trial involves 2 different treatments. Motivational Interviewing is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Intervention
Behavioral
Motivational interviewing intervention
Standard of CareStandard of Care
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Motivational interviewing
2016
Completed Phase 3
~7350

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline to 3 months post-intervention
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline to 3 months post-intervention for reporting.

Who is running the study

Principal Investigator
E. U.
Prof. Ebele Umeukeje, Assistant Professor of Medicine
Vanderbilt University Medical Center

Closest Location

Vanderbilt Dialysis Clinic - Nashville, TN

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 5 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
African American
Receiving hemodialysis treatments
Been on hemodialysis for more than 30 days
18 years of age and older
Within a 3-month look back at the time of screening, patients who have missed at least one dialysis session or shortened at least one dialysis session by 15 minutes.

Patient Q&A Section

Can kidney failure, chronic be cured?

"For patients with chronic kidney failure, the goal should be to keep their GFR as low as possible while minimizing toxicity. Current best practice is to use ACE inhibitor/ARB combination with a spironolactone and eplerenone as a second-line agent." - Anonymous Online Contributor

Unverified Answer

What are common treatments for kidney failure, chronic?

"Given the frequency and consequences of kidney failure, common treatments are plentiful and multifactorial. Common treatments include medications and dialysis, where dialysis may be lifesaving long-term therapy for a majority of patients, and hemodialysis, which may be indicated for patients with advanced kidney failure despite optimal therapy. Common treatments for anemia and hypothyroidism, chronic kidney disease, and the nephrostomy placement include medications, fluid optimization and dialysis. While patients may benefit from multiple strategies, nephrostomy placement is the most efficacious in long-term treatment for chronic kidney Disease, anemia, and hypothyroidism refractory to the other interventions." - Anonymous Online Contributor

Unverified Answer

How many people get kidney failure, chronic a year in the United States?

"Recent findings shows that in all age groups there are greater rates of kidney failure than the number of people with heart failure. This means that kidney failure is happening more often than heart failure each year in America. In men, kidney failure was about 3.7 times higher than the number of people with chronic heart failure. In women, kidney failure was almost twice as frequent.(ABSTRACT TRANSPLANT, J NURSEN, F DEGROEP, et al., "

"Diacanthina fusca\n\nDiacanthina fusca is a species of sea squirts, tunicates, marine invertebrates of the class Gastrotricha." - Anonymous Online Contributor

Unverified Answer

What causes kidney failure, chronic?

"There is a great deal of variability in the definition of chronic kidney disease. However, even a large range of definitions show that chronic kidney disease affects a considerable number of adults. The cause of kidney failure, chronic kidney disease and chronic kidney disease-specific morbidity and mortality all vary widely by definition. The impact of chronic kidney disease on morbidity and mortality can be significant. There is great variation between studies in both the prevalence and cause of this multi-factorial disease." - Anonymous Online Contributor

Unverified Answer

What are the signs of kidney failure, chronic?

"A number of signs of kidney failure relate to the underlying disease state. These include: weight gain, edema, raised BP, increased protein excretion, oliguria and an increased serum creatinine level with increased excretion of albumin or uromodulin. The clinical presentation and diagnosis will vary depending on the underlying cause. For the most part the clinical presentation resembles that of chronic kidney disease. The most commonly used tests used to exclude CKD are inadequate to do this. In summary, there are a number of common clinical signs of kidney failure, which are most easily recognized by most general clinicians." - Anonymous Online Contributor

Unverified Answer

What is kidney failure, chronic?

"An increased number of patients at risk are being identified as a result of improved screening. These patients are typically more ill and live progressively shorter lives, requiring longer hospital stays and greater health system expenditures. However, a number of clinical and demographic features are predicting the high morbidity and mortality and resource utilization of kidney failure, chronic. A focus on those specific clinical and demographic variables are required to effectively treat patients with organ failure at risk who require lifelong care." - Anonymous Online Contributor

Unverified Answer

How does motivational interviewing work?

"The use of motivational interviewing did not promote self-efficacy; however, it promoted the participants' understanding of the disease and its treatment, in addition to their general disease beliefs and beliefs regarding the utility of the treatment. Hence, the use of this technique could have potentially improved treatment adherence." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of kidney failure, chronic?

"Chronic kidney disease resulted from a combination of factors: aging, nondigestive disease, cardiovascular causes, and a growing population prone to nonrenal causes. The most common cause of chronic kidney disease in this population was cardiovascular disease." - Anonymous Online Contributor

Unverified Answer

Has motivational interviewing proven to be more effective than a placebo?

"M-I may be an effective intervention to increase exercise uptake in persons with chronic kidney disease and may assist in reducing distress during the transition to dialysis. Data from a recent study underscore the feasibility of using motivational interviewing strategies." - Anonymous Online Contributor

Unverified Answer

Does motivational interviewing improve quality of life for those with kidney failure, chronic?

"Improving patients' motivation for change improved patients' quality of life, but did not decrease it, suggesting that interventions that are currently used for this population would be most effective if used in combination." - Anonymous Online Contributor

Unverified Answer

Is motivational interviewing typically used in combination with any other treatments?

"The MIST is a valuable and useful tool in the treatment of patients with chronic kidney disease. MIST has a unique and beneficial method of improving motivation for treatment, increasing patient's awareness of their disease state and influencing patients to take up their medication. The use of MIST may further improve treatment adherence." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating kidney failure, chronic?

"There are many recent advances in treating chronic kidney failure and more research must be done. However, it still remains difficult for research to come up with treatments for the disease because the causes of the disease are still not well known. A new type of immunotherapy called [nivolumab] might help some patients with chronic kidney failure, but [nivolumab] is not FDA approved for [kidney failure] patients. Additionally, [nivolumab]'s FDA"

"Dicrossus\n\nDicrossus is a genus of bugs from the Pentatomidae family." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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