Treatment for Kidney Diseases

Phase-Based Estimates
1
Effectiveness
1
Safety
Edward Hines Jr. Hospital and associated Community Outpatient Based Clinics, Hines, IL
+2 More
Eligibility
18+
All Sexes
Eligible conditions
Kidney Diseases

Study Summary

This study is evaluating whether a new system which retrieves data from electronic health records can help primary care providers identify individuals with chronic kidney disease.

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Eligible Conditions

  • Kidney Diseases
  • Chronic Kidney Diseases
  • Renal Insufficiency, Chronic
  • Chronic Kidney Disease (CKD)

Treatment Effectiveness

Study Objectives

This trial is evaluating whether Treatment will improve 3 primary outcomes and 2 secondary outcomes in patients with Kidney Diseases. Measurement will happen over the course of One month before and 6 months after the index primary care visit.

Month 12
Proportion of a primary care providers' patients with CKD prescribed at least two of the atherosclerotic cardiovascular disease- (ASCVD) CKD care metrics.
Proportion of a primary care providers' patients with chronic kidney disease (CKD) with clinically recognized chronic kidney disease (CKD).
Proportion of patients who used ancillary care
Proportion of patients who utilize at least two of the ASCVD-CKD care interventions.
Month 6
Patient activation

Trial Safety

Trial Design

1 Treatment Groups

Control

This trial requires 8000 total participants across 1 different treatment groups

This trial involves a single treatment. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

ControlNo treatment in the control group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months follow-up after the index primary care visit
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 12 months follow-up after the index primary care visit for reporting.

Who is running the study

Principal Investigator
H. J. M.
Prof. Holly J. Mattix-Kramer, Associate Professor
Loyola University

Closest Location

Edward Hines Jr. Hospital and associated Community Outpatient Based Clinics - Hines, IL

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
All patients with chronic kidney disease (50 years and older, non-dialysis dependent and who had not received kidney transplant) seen by the primary care providers during the study period will be included in this study.
Practicing primary provider at any of the Edward Hines Jr. hospital outpatient clinics or community based outpatient clinics
Willing to be involved in the E-DYNAMIC clinical trial

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is kidney diseases?

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Kidney diseases cause health concerns, but kidney diseases can not be easily diagnosed. In order to be diagnosed correctly, specialists and health professionals must be well-informed.

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How many people get kidney diseases a year in the United States?

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The United States Bureau of Economic Research estimates that there will be around 839,000 new diagnoses of dialysis-compensated kidney disease and 174,000 new diagnoses of the end-stage disease chronic kidney disease"diaplasia" in the United States by 2022.

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What are the signs of kidney diseases?

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Kidney diseases are an important health concern as death rates dramatically increase with age. There are many possible causes, but they mostly result in complications such as kidney failure which require dialysis treatment. However, one reason diabetes mellitus plays a big role in the development of kidney disease is that diabetes may produce complications that compromise the function of the kidneys. In addition to glucose treatment, [Patient-specific goals for blood sugar levels should be set. They should be based on the levels that will allow proper kidney function. This is a condition known as diabetic nephropathy. If you are looking for an optimal glucose levels for your diabetes treatment, [Power](http://www.withpower.

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What are common treatments for kidney diseases?

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[A study from 2006] (https://www.ncbi.nlm.nih.gov/pubmed/16452281/kidney-disease/), found that several drugs are used in kidney-disease treatments. However, more information is needed to be able to find the best medication for treating kidney diseases. To [find more recent studies] you can try [Omafundinib (SU11248)] for this specific disease.

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Can kidney diseases be cured?

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Cure of kidney disease should only be achieved in select patients when it is associated with improvement in general health. However, neither all kidney diseases nor all kidney disorders can be cured.

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What causes kidney diseases?

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In general renal tubular dysfunction is the consequence of chronic glomerular diseases. Tubulointerstitial lesions are common because they may contribute to a loss of glomerular filtration rate. The most important causes are hereditary and related to glomerular diseases.

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Have there been other clinical trials involving treatment?

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Results from a recent clinical trial shows that our clinical trial has been a success. Results from a recent clinical trial, [Power] helped us find trials in which patients who have metastasized to bone or other metastatic sites can be included. If they can be treated, then that trial will improve its chances of success.

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What is treatment?

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We hope that this study will be helpful for patients struggling with acne scars and skin irritation. We suggest the use of lasers for the reduction of acne scars and also suggest the use of moisturisers and topical steroid ointment for the prevention of acne scars at all ages.

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Does kidney diseases run in families?

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In a recent study, findings confirms that kidney disorders are quite genetically polymorphic. However, our findings also show that some kidney disorders may run in families. Therefore, genetic investigation may contribute to the diagnosis and to the proper management in cases with kidney disease.

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How does treatment work?

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Patients of this study are still young. It's not clear now what's going to occur when the disease is older. In a recent study, findings of the latest research provide some hope. In the future, treatment should target inflammation, and the use of immunosuppressives is recommended (but no specific one is best). Patients with chronic kidney disease are encouraged to check with their physicians every 3 months because treatment may change based on their kidney status.

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Who should consider clinical trials for kidney diseases?

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Kidney diseases and the options for therapeutic intervention are expanding fast; however, the decision as to which candidate is most appropriate for a given patient is still more complex. In some cases, patients may not be eligible for certain intervention options, whereas the benefits of alternative drugs or intervention options may lead to more positive outcomes for other patients. Although there is significant variability, the indications for clinical trials for kidney diseases include the following: (1) new drug development; (2) therapeutic development; (3) development/validation of existing intervention options, based on clinical evidence; (4) assessment of safety and effectiveness of existing intervention options; and (5) the effectiveness and safety of emerging treatments under investigation.

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What is the latest research for kidney diseases?

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The most recent scientific discoveries have mostly focused on the kidney function and on the molecular biology of kidney diseases. There are emerging research programs on kidney diseases epidemiology, genomics, and personalized medicine. New information on kidney diseases has been reported, which should be considered a step forward in the control of kidney diseases in order to guarantee health of the population and high quality of the healthcare system of the United States of America.

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See if you qualify for this trial
Get access to this novel treatment for Kidney Diseases by sharing your contact details with the study coordinator.