Resistant Starch Diet for Chronic Kidney Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
The investigators want to learn more about how to help people who have chronic kidney disease (CKD). This study will increase the investigators understanding of how diet affects factors that can slow the progression of kidney disease. The investigators are asking 30 adults and 30 children with stage 3 CKD to be part of this study. Participants will supplement their diet with resistant starch for two weeks. The investigators anticipate that the resistant starch will change the bacteria in the intestines to a more beneficial type of bacteria. The investigators will measure a product of these beneficial bacteria called butyrate. The investigators will also determine changes in the gut bacteria and products of the bacteria in the blood.
Who Is on the Research Team?
John M Arthur, MD, Ph.D.
Principal Investigator
University of Arkansas
Are You a Good Fit for This Trial?
This trial is for adults aged 18-85 and children 5-17 with stage 3 chronic kidney disease (CKD), having specific levels of kidney function and protein in urine. Excluded are those under age 5 or over 85, with certain medical conditions like diabetes, recent antibiotic use, bowel diseases, past kidney transplants, pregnancy, or extreme bowel habits.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants supplement their diet with resistant starch for two weeks
Follow-up
Participants are monitored for changes in gut microbiome and blood uremic toxins
What Are the Treatments Tested in This Trial?
Interventions
- Resistant Starch
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Arkansas
Lead Sponsor
National Institutes of Health (NIH)
Collaborator
National Institute of General Medical Sciences (NIGMS)
Collaborator