← Back to Search

Cryoneurolysis (active) for Below Knee Amputation

N/A
Waitlist Available
Led By Brian Ilfeld, MD, MS
Research Sponsored by University of California, San Diego
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up months 1, 3, 6, and 12
Awards & highlights

Study Summary

This trial is testing if adding cryoanalgesia ( freezing the area around the surgery site) to standard pain relief care can decrease the severity and incidence of post-surgical pain, and improve postoperative functioning.

Eligible Conditions
  • Above Knee Amputation
  • Below Knee Amputation
  • Mastectomy
  • Shoulder Replacement Surgery
  • Knee Arthritis
  • Rotator Cuff Repair
  • Elbow Amputation
  • Skin Grafting
  • Video-assisted Thoracoscopic Surgery
  • Below Elbow Amputation

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~months 1, 3, 6, and 12
This trial's timeline: 3 weeks for screening, Varies for treatment, and months 1, 3, 6, and 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Average Pain (Mastectomy Subjects Only)
Secondary outcome measures
Analgesic Consumption
Average Pain Measured on the 11 Point Numeric Rating Scale
Brief Pain Inventory (Interference Subscale)
+10 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Treatment (active cryoneurolysis)Experimental Treatment1 Intervention
Receiving active cryoneurolysis
Group II: ShamPlacebo Group1 Intervention
Receiving sham cryoneurolysis procedure
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cryoneurolysis (active)
2018
N/A
~100

Find a Location

Who is running the clinical trial?

University of California, San DiegoLead Sponsor
1,120 Previous Clinical Trials
1,521,308 Total Patients Enrolled
Epimed InternationalUNKNOWN
1 Previous Clinical Trials
20 Total Patients Enrolled
Myoscience (prior to merger with Pacira Pharmaceuticals)UNKNOWN

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment for this research study ongoing?

"According to the clinicaltrials.gov database, this particular trial is no longer actively looking for participants. The research was initially posted on August 25th 2018 and last edited on August 29th 2022. Nevertheless, there are still 554 other studies with open recruitment at the present time."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study
Brian M. Ilfeld, MD, MS 2018. "Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03578237.
~15 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top