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Antioxidant

Melatonin for Ischemic Stroke

N/A
Waitlist Available
Led By Jonathan Greco, DO
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, week 1
Awards & highlights

Study Summary

This trial will compare levels of a protein involved in inflammation before and after taking melatonin, to see if the supplement can help reduce inflammation after a stroke.

Eligible Conditions
  • Ischemic Stroke
  • Stroke

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, week 1
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, week 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in serum Interleukin 6 (IL 6)

Side effects data

From 2014 Phase 2 trial • 40 Patients • NCT01114373
42%
Fatigue
39%
Early Morning Wakening
36%
Daytime drowsiness
11%
Weakness
11%
Dizziness
11%
Nausea
11%
Blurred vision
100%
80%
60%
40%
20%
0%
Study treatment Arm
Melatonin
Placebo

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Melatonin GroupExperimental Treatment1 Intervention
Participants will receive 3mg of melatonin at 18:00 (+/- one hour) each evening up to seven days or for the duration of his or her hospital stay.
Group II: No Melatonin GroupActive Control1 Intervention
Participants will receive no melatonin for the length of their hospital stay.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Melatonin
2014
Completed Phase 4
~1150

Find a Location

Who is running the clinical trial?

University of FloridaLead Sponsor
1,340 Previous Clinical Trials
715,705 Total Patients Enrolled
2 Trials studying Ischemic Stroke
55 Patients Enrolled for Ischemic Stroke
Jonathan Greco, DOPrincipal InvestigatorUniversity of Florida
Andreja Packard, MD, PhDPrincipal InvestigatorUniversity of Florida

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are seniors over the age of sixty permitted to join this experiment?

"The parameters of this trial delineates that suitable applicants should be aged between 18 and 85. According to research, there are 39 trials for people under the age of 18 and 1055 for those beyond 65 years old."

Answered by AI

Are researchers still recruiting participants for this investigation?

"According to clinicaltrials.gov, this trial is not presently enrolling patients. It was initially published on April 1st 2022 and the records were last updated February 3rd 2022. Nevertheless, there are over one thousand other studies currently looking for volunteers in similar fields of research."

Answered by AI

What particular criteria must potential participants meet to qualify for this experiment?

"This medical intervention is available to individuals aged 18-85 who have suffered a wake-up stroke. 45 patients are being recruited for the study."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Melatonin in Acute Stroke
2022. "Melatonin in Acute Stroke". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03843008.
~0 spots leftby Apr 2025
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