All > Melatonin
Antioxidant

Melatonin for Ischemic Stroke

University of Florida College of Medicine-Jacksonville, Jacksonville, FL
Targeting 3 different conditionsMelatoninN/AWaitlist AvailableLed by Jonathan Greco, DOResearch Sponsored by University of Florida

Study Summary

This trial will compare levels of a protein involved in inflammation before and after taking melatonin, to see if the supplement can help reduce inflammation after a stroke.

Eligible Conditions
  • Ischemic Stroke
  • Stroke

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, week 1
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, week 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in serum Interleukin 6 (IL 6)

Side effects data

From 2014 Phase 2 trial • 40 Patients • NCT01114373
42%
Fatigue
39%
Early Morning Wakening
36%
Daytime drowsiness
11%
Dizziness
11%
Nausea
11%
Weakness
11%
Blurred vision
100%
80%
60%
40%
20%
0%
Study treatment Arm
Melatonin
Placebo

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Melatonin GroupExperimental Treatment1 Intervention
Participants will receive 3mg of melatonin at 18:00 (+/- one hour) each evening up to seven days or for the duration of his or her hospital stay.
Group II: No Melatonin GroupActive Control1 Intervention
Participants will receive no melatonin for the length of their hospital stay.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Melatonin
2014
Completed Phase 4
~1150

Find a site

Who is running the clinical trial?

University of FloridaLead Sponsor
1,295 Previous Clinical Trials
703,778 Total Patients Enrolled
2 Trials studying Ischemic Stroke
55 Patients Enrolled for Ischemic Stroke
Jonathan Greco, DOPrincipal Investigator
University of Florida
Andreja Packard, MD, PhDPrincipal Investigator
University of Florida

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are seniors over the age of sixty permitted to join this experiment?

"The parameters of this trial delineates that suitable applicants should be aged between 18 and 85. According to research, there are 39 trials for people under the age of 18 and 1055 for those beyond 65 years old."

Answered by AI

Are researchers still recruiting participants for this investigation?

"According to clinicaltrials.gov, this trial is not presently enrolling patients. It was initially published on April 1st 2022 and the records were last updated February 3rd 2022. Nevertheless, there are over one thousand other studies currently looking for volunteers in similar fields of research."

Answered by AI

What particular criteria must potential participants meet to qualify for this experiment?

"This medical intervention is available to individuals aged 18-85 who have suffered a wake-up stroke. 45 patients are being recruited for the study."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Melatonin in Acute Stroke
2022. "Melatonin in Acute Stroke". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03843008.
~18 spots leftby Oct 2024
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