Treatment for Intervertebral Disc Displacement

Waitlist Available · 18+ · All Sexes · Winnipeg, Canada

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About the trial for Intervertebral Disc Displacement

Eligible Conditions
Lumbar Herniated Disc · Intervertebral Disc Displacement

Treatment Groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Control Group 1
Control Group 2


This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Subjects will be between the ages of 18 and 90.
Male and female subjects will be recruited into the study.
All patients will clinically demonstrate unilateral lower extremity pain in greater proportion to low back pain symptoms if present. Imaging (CT) will document single level lumbar herniated nucleus pulposis.
Subjects participating will be required to speak and read English.
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: continuous for 3 weeks postoperatively
Screening: ~3 weeks
Treatment: Varies
Reporting: continuous for 3 weeks postoperatively
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: continuous for 3 weeks postoperatively.
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Trial Expert
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- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Treatment will improve 1 primary outcome in patients with Intervertebral Disc Displacement. Measurement will happen over the course of continuous for 3 weeks postoperatively.

Physical activity monitor

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes intervertebral disc displacement?

Intervertebral disc displacement is a complex disease. It is estimated that >80% of intervertebral disc displacement cases are the result of an external traumatic event. However, the exact mechanism is unclear. Possible causes include anatomical abnormality of the intervertebral disc, abnormal nerve signalling at rest, and disruption to growth plate cartilage. All of these factors may relate to the altered tissue homeostasis or altered joint loading during disc displacement.

Anonymous Patient Answer

Can intervertebral disc displacement be cured?

Although these results were from a small sample of patients with the most difficult disease-state, many patients experienced a significant reduction in pain, disability, and fear of surgery immediately following surgery. The data do not allow for conclusions on the ability of surgery to cure intervertebral disc displacement.

Anonymous Patient Answer

How many people get intervertebral disc displacement a year in the United States?

The number of people who have suffered an intervertebral disc disruption who require a lumbar fusion operation is about 16,500. The lifetime loss of work due to disc displacement is estimated to be at least $3 billion/year in the United States.

Anonymous Patient Answer

What are common treatments for intervertebral disc displacement?

While surgery is often effective at reducing symptoms, it provides little benefit in preventing intervertebral disc degeneration or decreasing the incidence of radiculopathy. While surgery can provide relief from acute symptoms, it seldom helps prevent chronic degeneration or prevents the need for repeat treatment. In addition, surgery provides no measurable benefit in avoiding low back pain.

Anonymous Patient Answer

What is intervertebral disc displacement?

Because the disc appears to be a continuous fluid-filled cavity, the presence of abnormal motion outside the normal range of disc motion could result in pain and disability. An intact intervertebral joint will typically move within the normal range of motion, but there could still be disc displacement. If pain and disability originate outside the normal range of motion, they could be caused by tear of the posterior or anterior annulus fibers or displacement of the nucleus into the spinal canal. Posterior disc displacement resulting from lumbar spinal stenosis is commonly seen on lumbosacral spine X-ray. When the posterior disc displacement is seen with an anterior disc displacement, it is highly suggestive of lumbosacral spinal stenosis.

Anonymous Patient Answer

What are the signs of intervertebral disc displacement?

Weakness, pain and tingling of extremities may be present in disc-displacement, particularly of the L4/5 lesion. X-rays are helpful to detect a compression of the sciatic canal or of the femoral nerves. Nerve conduction studies are highly recommended to detect the compression of the femoral nerves.

Anonymous Patient Answer

How serious can intervertebral disc displacement be?

Disc displacement is highly variable in severity and can result in disability or death. Disc displacement occurs when one vertebra slides, or bulges, upon the adjacent vertebrae. Usually, pain results in disc displacement, often being referred to the lower back and shoulder areas. In severe cases, disc displacement can become chronic, resulting in a number of complications, such as muscle damage and even nerve damage, which may result in numbness and weakness. The severity of the pain will be related to the condition of the individual and the exact severity of their disc displacement. The exact level of pain will depend on the area of the spine, as well as the location of the disc displacement.

Anonymous Patient Answer

Who should consider clinical trials for intervertebral disc displacement?

Patients with suspected spinal disk herniations, with radiologic findings that suggest the need for surgery, and with a history of recent back pain are likely to benefit from therapeutic interventions. Clinical trial methodology should include all the above indicators of the disorder being studied, as more patients would probably benefit from the intervention.

Anonymous Patient Answer

What is the primary cause of intervertebral disc displacement?

Anterior annular tears were found to be one of the major etiologies of IAD. Because disc displacement has been found to be associated with radiculopathy, a correct diagnosis of IAD is a medical priority. Patients should be questioned about back pain, sciatica, disc herniation, prior surgeries, and other potential causes of disc herniation. In addition, to confirm the primary etiology, magnetic resonance imaging (MRI) can be indicated.

Anonymous Patient Answer

Does intervertebral disc displacement run in families?

Recent findings suggest that DDD does not have an identifiable genetic component, because of the low relative risk associated with the disease. Recent findings also support the hypothesis that disc degeneration does not have a genetic component.

Anonymous Patient Answer

Have there been any new discoveries for treating intervertebral disc displacement?

Although treatments have been developed to address all cases of spondylolisthesis including facet joint degeneration, disc degeneration, and disc rupture, there are limited studies and randomized trials evaluating their efficacy for treating the clinical presentation of spinal disorders.

Anonymous Patient Answer

How does treatment work?

The effectiveness of treatment in this study was low, and our findings are of concern (suggestive, suggestive, or highly suggestive for ILD). In order to more clearly elucidate the clinical effect of a treatment one must determine whether this new treatment can alter the natural history of a specific disease, or are there other treatment options that can be employed before treatment with a medication or procedure is initiated.

Anonymous Patient Answer
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