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Tissue Transplantation

Active Allograft for Degenerative Disc Disease (VAST Trial)

N/A
Waitlist Available
Research Sponsored by Vivex Biomedical, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 and 12 months
Awards & highlights

VAST Trial Summary

This study is evaluating whether a viable allograft can be injected into the nucleus pulposus of a degenerated disc to treat back pain.

Eligible Conditions
  • Degenerative Disc Disease

VAST Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 and 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Visual Analogue Scale of Pain Intensity (VASPI)
Secondary outcome measures
36-Item Short Form Survey (SF-36) Questionnaire
Adverse Events (AEs) and Serious Adverse Events (SAEs)
MRI Assessments
+3 more

VAST Trial Design

3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Active AllograftExperimental Treatment1 Intervention
Injection of viable allograft
Group II: Conservative CareActive Control1 Intervention
Continued conservative care treatment
Group III: PlaceboPlacebo Group1 Intervention
Injection of saline

Find a Location

Who is running the clinical trial?

Vivex Biomedical, Inc.Lead Sponsor
5 Previous Clinical Trials
10,102 Total Patients Enrolled
VIVEX Biologics, Inc.Lead Sponsor
7 Previous Clinical Trials
10,602 Total Patients Enrolled
Timothy Ganey, PhDStudy DirectorVIVEX Biologics, Inc.

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain
2017. "Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03709901.
All > Low Back Pain > Back Pain
~28 spots leftby Apr 2025
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