This trial is evaluating whether B=No Breakfast will improve 7 primary outcomes in patients with Insulin Resistance. Measurement will happen over the course of 0min to 420 min during both during the treatment and control visits over the one year study period. Each study visit will be conducted on 2 separate days with a washout period of at least 1 week in between the study visits for each patient.
This trial requires 24 total participants across 2 different treatment groups
This trial involves 2 different treatments. B=No Breakfast is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"Insulin resistance cannot be cured and cannot be an exclusive cause of diabetes or other dysmetabolic (metabolic) disorders. Treating metabolic disorders such as insulin resistance or diabetes in isolation can often worsen the metabolic and/or cardiovascular consequences of the condition." - Anonymous Online Contributor
"Insulin resistance occurs in about a quarter of people without any personal risk factors for Type 2 Diabetes. It may be that genes play a role. More research is now needed to clarify its mechanism and to identify children at risk before development of Type 2 diabetes." - Anonymous Online Contributor
"The most common treatment for non-diabetic insulin resistance, including cases with insulin resistance, is exercise combined with caloric restriction, weight loss and a change in diet pattern. These therapies do not decrease the risk for developing type 2 diabetes or cardiovascular diseases." - Anonymous Online Contributor
"It is estimated that one of every five, twenty-three of every eight persons, and forty-five thousand women in the United States are insulin resistant. A disproportionate percentage of these people are black or Hispanic." - Anonymous Online Contributor
"Insulin resistance (IR) is a condition marked by a marked increase in plasma glucose in the setting of a normal or high plasma insulin response to a glucose load. In people with IR insulin secretion decreases and plasma glucose tolerance may be low, even if plasma insulin levels remain within normal limits.\n" - Anonymous Online Contributor
"The signs of insulin resistance include high body mass index, lack of oral hypoglycemia, poor glucose tolerance, high glycemic indices, high total and free triglyceride." - Anonymous Online Contributor
"In daily practice, an elevated fasting insulin level was the most important predictive parameter for the likelihood of an individual having a b=no breakfast. Fasting insulin was also a significant predictor for the number of hypoglycaemic episodes during the year following an elevated fasting insulin level." - Anonymous Online Contributor
"For every 3 hours of sleep in an adults age 70-80 years old, a 0.5 kg decrease in body weight is observed. Furthermore, this is even more evident in men. After one meal or a fat-free breakfast, a 2.8% extra weight loss is noticed even in women. If the main hypothesis is true, one would expect obese men to lose less weight. However, in this cohort, overweight status is not associated with higher body fat." - Anonymous Online Contributor
"The majority of clinical trials for insulin resistance and cardiometabolic disease have poor or no methodology. Clinical trials with poor study design will not demonstrate differences between treatment groups. Randomized clinical trials are thus advised to be conducted for cardio-metabolic disease, insulin resistance, end-stage disease with comorbidities, and other related conditions. However, the importance of clinical trials for insulin resistance, especially those with good-quality design, cannot be underestimated." - Anonymous Online Contributor
"The increase in insulin resistance after consuming a b=no breakfast is consistent with earlier research on mixed meals. This increase is also evident when consuming a high-fiber bread product." - Anonymous Online Contributor
"At the same time, it should remember that new indications have no effect on the development of drug interactions. Drug interactions are only a factor to limit." - Anonymous Online Contributor
"'Side effect' can include many different aspects of the patient's life, with no single'side effect' accounting for many problems. While some side effects affect more than one other thing, some side effects can affect more than one part of a person's life." - Anonymous Online Contributor