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Exercise for Type 2 Diabetes (DYNAMMO-T2DEX Trial)

N/A

Waitlist Available

Led By John Kirwan, PhD

Research Sponsored by Pennington Biomedical Research Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Type 2 Diabetes

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 5 years

Awards & highlights

DYNAMMO-T2DEX Trial Summary

This trial looks at the relationship between how well cells process sugar and fats, and the development of type 2 diabetes.

Who is the study for?

This trial is for adults with Type 2 Diabetes who have a Body Mass Index (BMI) between 25 and 40 kg/m², an HbA1C level below 8.5%, and lead a sedentary lifestyle. It's not open to those currently on diabetes medication or smokers.Check my eligibility

What is being tested?

The study investigates how exercise affects the mitochondria in muscle cells of people with Type 2 Diabetes, which could influence insulin resistance and blood sugar levels, potentially leading to new treatments.See study design

What are the potential side effects?

Since the intervention being studied is exercise, potential side effects may include typical post-exercise symptoms such as muscle soreness, fatigue, or mild discomfort.

DYNAMMO-T2DEX Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have Type 2 Diabetes.

DYNAMMO-T2DEX Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Effects of exercise on mitochondrial dynamics

Secondary outcome measures

Effects of exercise on mitochondrial function

Insulin sensitivity

DYNAMMO-T2DEX Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: exerciseExperimental Treatment1 Intervention

12 week exercise program, 5 days/week, 60 min/day

Group II: standard of careActive Control1 Intervention

12 week standard of care recommendations

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

exercise

2014

Completed Phase 4

~1190

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Pennington Biomedical Research CenterLead Sponsor

304 Previous Clinical Trials

181,412 Total Patients Enrolled

7 Trials studying Diabetes

1,433 Patients Enrolled for Diabetes

John Kirwan, PhDPrincipal Investigator - Pennington Biomedical Research Center

Pennington Biomedical Research Center

3 Previous Clinical Trials

356 Total Patients Enrolled

Media Library

Exercise Clinical Trial Eligibility Overview. Trial Name: NCT02977442 — N/A

Diabetes Research Study Groups: exercise, standard of care

Diabetes Clinical Trial 2023: Exercise Highlights & Side Effects. Trial Name: NCT02977442 — N/A

Exercise 2023 Treatment Timeline for Medical Study. Trial Name: NCT02977442 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this investigation restrict participants to those aged 80 or below?

"This study stipulates that prospective participants should be in between 18 and 50 years old. 205 trials are available for minors, while those above 65 can access 946 clinical trials."

Answered by AI

How many experimental subjects are taking part in this clinical trial?

"Affirmative. Clinicaltrials.gov hosts data which confirms this medical study, initially posted on November 1st 2016, is actively recruiting participants. Currently it seeks to enroll 60 patients from one site."

Answered by AI

Could I potentially join this experiment as an individual?

"To qualify for this trial, individuals must possess insulin resistance and fall within the 18 to 50 year age bracket. Altogether, 60 participants are required."

Answered by AI

Are there any current openings to join this experiment?

"Affirmative. The clinicaltrials.gov webpage reveals that this experiment is currently enrolling subjects, which began on November 1st 2016 and has been updated as of September 7th 2022. 60 individuals are needed for the study at one site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise

John Kirwan 2016. "Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02977442.

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