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Exercise for Insulin Resistance
N/A
Recruiting
Led By William Schrage, PhD
Research Sponsored by University of Wisconsin, Madison
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Age 12-18 years inclusive
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 1 day
Awards & highlights
Study Summary
This trial looks at how insulin resistance (IR) affects cognition and brain blood vessels in adolescents, to see if it has a negative effect.
Who is the study for?
This trial is for typically developing adolescents aged 12-18 without diabetes, neurological or developmental disorders, significant head injuries, or severe medical conditions. Participants must not be pregnant, currently smoking heavily, on insulin treatment, or have a weight below 94.5 lbs.Check my eligibility
What is being tested?
The study investigates how brain blood vessel function and cognitive abilities are affected by varying levels of insulin resistance in adolescents using tests like cognitive assessments and monitoring changes during exercise on a cycle ergometer.See study design
What are the potential side effects?
Since the interventions include non-invasive procedures such as cognitive tests and physical activity on an exercise bike, side effects may be minimal but could include discomfort from wearing testing equipment or fatigue from the exercises.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am between 12 and 18 years old.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 1 day
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 1 day
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Cerebral blood flow as determined by TCD
Cognitive Function as determined by NIH Dimensional Change Card Sorting Test
Cognitive Function as determined by NIH Flanker Inhibitory Control and Attention Test
+6 moreTrial Design
1Treatment groups
Experimental Treatment
Group I: Enrolled, eligibleExperimental Treatment4 Interventions
Single arm for eligible subjects
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Doppler
2018
Completed Phase 1
~810
Cycle ergometer
2016
N/A
~60
Find a Location
Who is running the clinical trial?
University of Wisconsin, MadisonLead Sponsor
1,183 Previous Clinical Trials
3,167,534 Total Patients Enrolled
5 Trials studying Insulin Resistance
407 Patients Enrolled for Insulin Resistance
William Schrage, PhDPrincipal InvestigatorUniversity of Wisconsin, Madison
2 Previous Clinical Trials
162 Total Patients Enrolled
1 Trials studying Insulin Resistance
18 Patients Enrolled for Insulin Resistance
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You cannot have an MRI scan.My physical development is before Tanner Stage 3.You have a neurological or developmental disorder such as intellectual disability or autism.I have been diagnosed with kidney, lung, or heart disease, but not asthma requiring daily or pre-exercise medication.I have not had a significant head injury or conditions like concussion.I am between 12 and 18 years old.I weigh less than 94.5 lbs.The principal investigator decides that there are other reasons you cannot participate in the study.I am on insulin or drugs that increase insulin sensitivity.My mental development and cognitive abilities are normal.I have diabetes with a fasting glucose level of 126 mg/dL or higher.You have smoked nicotine more than five times in the past month.
Research Study Groups:
This trial has the following groups:- Group 1: Enrolled, eligible
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are elderly individuals eligible to join this scientific investigation?
"To join this medical trial, patients must have an age between 12 and 18. For those younger than 12 years old, there are 26 different studies available; alternatively, for seniors over 65 years of age there are 91 alternative trials to choose from."
Answered by AI
What criteria must I meet to qualify for participation in this experiment?
"This research endeavor is looking for 20 participants aged between twelve and eighteen who are cognitively sound and have been diagnosed with insulin resistance."
Answered by AI
Are there any opportunities for volunteers to partake in this experiment?
"Affirmative. Clinicaltrials.gov has the most recent details on this trial, which was originally posted in February of 2020 and updated as recently as July 6th 2022. As it stands currently, 20 participants are being recruited from one location to take part in this research endeavour."
Answered by AI
What is the sample size of participants involved in this clinical experiment?
"Affirmative. According to the information hosted on clinicaltrials.gov, this study is actively seeking participants since its initial posting on February 28th 2020; it was last updated on July 6th 2022 and requires 20 patients from a single site."
Answered by AI
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