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Behavioural Intervention

Advanced Meditation (Samyama) for Mental Health Wellness

N/A

Waitlist Available

Led By Senthilkumar Sadhasivam, MD

Research Sponsored by Indiana University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 months

Awards & highlights

Study Summary

This trial will investigate the effects of the Samyama program on neurotransmitters and the mind/psyche.

Who is the study for?

This trial is for adults over 18 who are advanced meditation program participants or their live-in spouses/significant others. It's not for those who can't understand the consent form, have conditions making blood draws unsafe, live outside the country, recently used certain supplements or antibiotics, or use marijuana/opioids.Check my eligibility

What is being tested?

The study examines how an advanced meditation technique called Samyama affects neurotransmitters and mental states. Participants undergo a preparatory phase with diet and yoga before testing through surveys and sample collection to see if there's less gut inflammation and improved wellbeing.See study design

What are the potential side effects?

Since this trial involves meditation practices rather than medication, traditional side effects are not expected. However, changes in consciousness levels during deep meditation could potentially cause unusual sensations or emotional responses.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Epigenetic analysis (DNA methylation)

Levels of Brain Derived Neurotrophic Factor (BDNF)

Transcriptome analysis

+1 more

Secondary outcome measures

Gut Inflammation analysis

Microbiome analysis

Plasma

Other outcome measures

EEG

fMRI

Trial Design

4Treatment groups

Experimental Treatment

Group I: Timepoint 4: 3 months Post SamyamaExperimental Treatment2 Interventions

Blood draw at home by at home phlebotomist Post program online survey follow up to be completed Survey link for participant Survey link for spouse: https Stool collection from home

Group II: Timepoint 3: Immediate Post-SamyamaExperimental Treatment3 Interventions

Online survey to be completed Survey link for participant Survey link for spouse Blood sample collection: on site at IIIS o Participant only - Not spouse/significant other. EEG and fMRI

Group III: Time point 2: Post-Preparatory/Pre-SamyamaExperimental Treatment3 Interventions

Online Surveys Participant Spouse Stool collection from IIIS/home Blood sample collection: on site at IIIS/home EEG and fMRI

Group IV: Time Point 1: Baseline/Pre-preparatory SamyamaExperimental Treatment2 Interventions

Survey link for participant Survey link for spouse/ "control" Stool collection from home Blood sample at home provided by at home phlebotomy services or at Isha Center group meditation by study personnel.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Indiana UniversityLead Sponsor

980 Previous Clinical Trials

982,402 Total Patients Enrolled

University of PittsburghLead Sponsor

1,719 Previous Clinical Trials

16,341,582 Total Patients Enrolled

Senthilkumar Sadhasivam, MDPrincipal InvestigatorIndiana University

Media Library

Samyama (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT04366544 — N/A

Happiness Research Study Groups: Timepoint 4: 3 months Post Samyama, Time Point 1: Baseline/Pre-preparatory Samyama, Time point 2: Post-Preparatory/Pre-Samyama, Timepoint 3: Immediate Post-Samyama

Happiness Clinical Trial 2023: Samyama Highlights & Side Effects. Trial Name: NCT04366544 — N/A

Samyama (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04366544 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still positions available for participants in this clinical trial?

"As per the clinicaltrials.gov database, this medical experiment is not presently taking on new participants - its initial posting was January 19th 2018 and it's latest update happened November 16th 2022. However, there are 1476 other studies that are actively searching for enrollees at present."

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