Organic grass-fed beef for Inflammation

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Nutrition Research Laboratory, Bozeman, MT
Inflammation+1 More
Organic grass-fed beef - Behavioral
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

Western omnivore diets tend to use beef as a good source of protein. Studies have shown cattle who are fed different diets results in varying nutritional meat profiles in terms of amino acids, types and relative amounts of fat, and other nutrients. While overlap between organic and conventionally raised beef is expected, dietary impacts on human health are potentially meaningful as small changes in diet may have large downstream effects on human metabolism. To date, no studies have been conducted in humans that evaluate the health effects of organic grass-fed beef consumption to conventionally-fed beef consumption. To fill this gap in research, the investigators propose to identify metabolic differences in response to consumption of organic grass-fed compared to conventional-fed beef on a wide array of blood borne nutrients including amino acids, lipids, bile acids, and hundreds of other metabolites. This comprehensive analysis is expected to differentiate nutritional and metabolic impacts relevant to human health and provide a foundation for future research. The purpose of this study is to determine how a beef steak meal may affect bile acids in the gut, inflammation, and the metabolic health of healthy individuals. This research will investigate the following questions: How do specific foods affect bile acids in the blood? How do specific foods changes inflammation, metabolism, and other health measures? If researchers learn how food affects different health related markers in the blood and how that may influence health, then this information can be used to do more research to improve the health of people in a future study.

Eligible Conditions

  • Inflammation
  • Healthy Subjects (HS)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Inflammation

Study Objectives

4 Primary · 4 Secondary · Reporting Duration: 1 day

1 day
Postprandial Eicosanoids
Postprandial serum bile acid concentration
Postprandial serum glucose
Postprandial serum inflammatory cytokines
Postprandial serum insulin
Postprandial serum lipidome and metabolome features (Untargeted)
Postprandial serum lipids
Postprandial serum metabolome features (Targeted amino acids)

Trial Safety

Safety Progress

1 of 3

Other trials for Inflammation

Trial Design

2 Treatment Groups

Conventional-fed beef, then organic grass-fed beef
1 of 2
Organic grass-fed beef, then conventional-fed beef
1 of 2
Experimental Treatment

10 Total Participants · 2 Treatment Groups

Primary Treatment: Organic grass-fed beef · No Placebo Group · N/A

Conventional-fed beef, then organic grass-fed beefExperimental Group · 2 Interventions: Organic grass-fed beef, Conventional-fed beef · Intervention Types: Behavioral, Behavioral
Organic grass-fed beef, then conventional-fed beefExperimental Group · 2 Interventions: Organic grass-fed beef, Conventional-fed beef · Intervention Types: Behavioral, Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1 day
Closest Location: Nutrition Research Laboratory · Bozeman, MT
Photo of montana 1Photo of montana 2Photo of montana 3
2019First Recorded Clinical Trial
5 TrialsResearching Inflammation
1 CompletedClinical Trials

Who is running the clinical trial?

Montana State UniversityLead Sponsor
37 Previous Clinical Trials
1,042,501 Total Patients Enrolled
6 Trials studying Inflammation
183 Patients Enrolled for Inflammation
Organic Advisory and Education CouncilUNKNOWN
Mary Miles, PhDPrincipal InvestigatorMontana State University
1 Previous Clinical Trials
48 Total Patients Enrolled
1 Trials studying Inflammation
48 Patients Enrolled for Inflammation

Eligibility Criteria

Age 18 - 65 · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have a body mass index between 18-27 kg/m^2.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.