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Uterine Scratching for Infertility

N/A

Waitlist Available

Led By Louise Lapensee, Md

Research Sponsored by Clinique Ovo

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

An IUI prescription

Unexplained infertility for over 12 months if under 35 years old or over 6 months if 35 years old and above.

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months for all 3 intrauterine insemination

Awards & highlights

Study Summary

This trial will test if uterine injury during the follicular phase of an intra-uterine insemination cycle helps with pregnancy rates during the first trimester ultrasound.

Who is the study for?

This trial is for people under 35 with unexplained infertility for over a year, or over 6 months if they're 35+. They must have at least one open fallopian tube and a normal uterine cavity. Men should have normal or mildly affected fertility. Those who've had invasive uterine procedures recently, severe endometriosis, irregular cycles due to PCOS, or need donor sperm can't join.Check my eligibility

What is being tested?

The study tests whether 'uterine scratching' (a minor injury to the uterus lining) during the follicular phase helps increase ongoing pregnancy rates in the first trimester after intra-uterine insemination (IUI).See study design

What are the potential side effects?

Uterine scratching may cause discomfort, cramping, bleeding similar to menstrual periods, and there's a small risk of infection following the procedure.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have a prescription for intrauterine insemination (IUI).

Select...

I have been unable to conceive for over a year if under 35, or over 6 months if 35 or older.

Select...

I have been unable to conceive for over a year if under 35, or over 6 months if 35 or older.

Select...

My uterine cavity is normal.

Select...

My uterine cavity is normal.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months for all 3 intrauterine insemination

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months for all 3 intrauterine insemination

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for all 3 intrauterine insemination for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Efficacy - Pregnancy Rate measured during the first trimester ultrasound.

Secondary outcome measures

Efficacy - Secondary pregnancy rate.

Safety - Complications

Safety - Side effects

Trial Design

2Treatment groups

Active Control

Group I: Endometrial scratching groupActive Control1 Intervention

Endometrial scratching will be done with a Pipelle in uterus.

Group II: Control groupActive Control1 Intervention

This group will proceed with intrauterine insemination without endometrial scratching according to clinic's standard procedure

0 / 5Eligibility criteria met

Find a Location

Who is running the clinical trial?

Clinique OvoLead Sponsor

31 Previous Clinical Trials

41,113 Total Patients Enrolled

Louise Lapensee, MdPrincipal InvestigatorClinique Ovo

Media Library

Endometrial Scratching (Other) Clinical Trial Eligibility Overview. Trial Name: NCT03828786 — N/A

Unexplained Infertility Research Study Groups: Endometrial scratching group, Control group

Unexplained Infertility Clinical Trial 2023: Endometrial Scratching Highlights & Side Effects. Trial Name: NCT03828786 — N/A

Endometrial Scratching (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03828786 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

For whom is this research opportunity available?

"Aspiring participants of this clinical trial must satisfy two criteria: they need to fall between the ages 18-41 and be diagnosed with infertility. All in all, 394 individuals are needed for recruitment."

Answered by AI