Sufficient physical activity for Sterility, Female

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Sterility, Female+1 More
Sufficient physical activity - Behavioral
Eligibility
18 - 65
Female
What conditions do you have?
Select

Study Summary

This trial will test if recommended weekly physical activity during ovarian stimulation affects mental health or clinical outcomes differently for active, insufficiently active, or inactive people. The goal is to see if physical activity during fertility treatment is safe and has value.

Eligible Conditions
  • Sterility, Female

Treatment Effectiveness

Study Objectives

3 Primary · 8 Secondary · Reporting Duration: 10 months

10 months
Live Birth Rate
14 days
Anxiety/Depression During Treatment based on Patient-Reported Outcomes Measurement Information System Short Form (PROMIS-SF) Depression 4a and Anxiety 4a
Stress During Treatment based on daily end of day stress item
2 weeks
Cancellation Rate
4 months
Treatment continuation rate
4 weeks
Blastulation Rate
Change in Stress during treatment based upon Perceived Stress Scale (PSS)-14
Fertilization Rate
Number of mature oocytes retrieved
6 weeks
Clinical Pregnancy Rate
Ovarian Torsion

Trial Safety

Trial Design

4 Treatment Groups

Usually Active- Decrease
1 of 4
Usually Insufficiently Inactive- Maintenance
1 of 4
Usually Active- Maintenance
1 of 4
Usually Insufficiently Inactive- Increase
1 of 4
Active Control
Experimental Treatment

600 Total Participants · 4 Treatment Groups

Primary Treatment: Sufficient physical activity · No Placebo Group · N/A

Usually Active- Maintenance
Behavioral
Experimental Group · 1 Intervention: Sufficient physical activity · Intervention Types: Behavioral
Usually Insufficiently Inactive- Increase
Behavioral
Experimental Group · 1 Intervention: Sufficient physical activity · Intervention Types: Behavioral
Usually Active- Decrease
Behavioral
ActiveComparator Group · 1 Intervention: Insufficient physical activity · Intervention Types: Behavioral
Usually Insufficiently Inactive- Maintenance
Behavioral
ActiveComparator Group · 1 Intervention: Insufficient physical activity · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 10 months

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor
2,262 Previous Clinical Trials
11,469,504 Total Patients Enrolled
Heather Huddleston, MDPrincipal InvestigatorUniversity of California, San Francisco
5 Previous Clinical Trials
11,152 Total Patients Enrolled

Eligibility Criteria

Age 18 - 65 · Female Participants · 3 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are a patient at the Center for Reproductive Health, University of California San Francisco.
You have had one or more ovarian stimulation cycles.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 20th, 2021

Last Reviewed: October 26th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

Who else is applying?

What state do they live in?
California60.0%
South Carolina10.0%
North Carolina10.0%
Other20.0%
How old are they?
18 - 65100.0%
What site did they apply to?
UCSF Medical Center at Mission Bay100.0%
What portion of applicants met pre-screening criteria?
Met criteria60.0%
Did not meet criteria40.0%

How responsive is this trial?

Most responsive sites:
  1. UCSF Medical Center at Mission Bay: < 24 hours
Typically responds via
Email100.0%
Average response time
  • < 1 Day