Far-UVC Light for Respiratory Infections
(PRiVII Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether a special type of ultraviolet light, called far-UVC, can reduce the spread of viruses causing respiratory infections, such as the flu and COVID-19, in long-term care facilities. It focuses on elderly residents who may struggle with standard infection control methods due to memory issues and shared spaces. The trial compares far-UVC light as a disinfectant with a regular fluorescent light that lacks disinfectant properties. Residents in long-term care who agree to data collection might be suitable for this study. As an unphased trial, it offers participants the chance to contribute to innovative research that could improve infection control in vulnerable populations.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that this far-UVC light is safe for disinfection?
Research has shown that far-UVC light is both effective and safe for humans. Studies have found that far-UVC light, particularly at 222 nm, can kill germs without damaging human skin or eyes. This is crucial because regular ultraviolet light can be harmful if used directly. Tests in indoor places like hospitals have confirmed that far-UVC light remains safe even with long-term exposure. It effectively kills airborne viruses, helping to reduce infection spread. To date, no significant harmful effects have been reported with far-UVC light, making it a promising option for additional disinfection.12345
Why are researchers excited about this trial?
Researchers are excited about the potential of Far-UVC light for respiratory infections because it offers a unique method of disinfection. Unlike traditional chemical disinfectants or antibiotics, Far-UVC light can inactivate viruses and bacteria in the air without harming human skin or eyes, thanks to its specific wavelength. This means it could provide continuous, safe, and effective disinfection in public spaces, potentially reducing the spread of infections more efficiently than current methods.
What evidence suggests that far-UVC light is effective for respiratory infections?
Research has shown that Far-UVC light can kill viruses in the air and on surfaces. Studies have found that Far-UVC light, with a wavelength of 222 nm, deactivates viruses like those causing COVID-19 and the flu. This light damages the virus's genetic material, preventing it from spreading. It is as effective as other germ-killing lights but safer for people. In this trial, participants will be exposed to Far-UVC light as an additional disinfection method, which could help reduce viral infections, especially in long-term care facilities.678910
Who Is on the Research Team?
Kenneth Rockwood, MD
Principal Investigator
Nova Scotia Health Authority
Are You a Good Fit for This Trial?
This trial is for elderly residents in long-term care facilities who are at higher risk of respiratory viral infections like the flu and COVID-19. Participants must consent to join the study, which aims to test additional disinfection methods.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Far-UVC light is used as an additional method of disinfection in common areas of long-term care facilities
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Far-UVC Light
Trial Overview
The study is testing far-UVC light as an extra disinfection method against viruses that cause respiratory infections. It will be compared with a placebo fluorescent light to see if it's more effective in preventing illness.
How Is the Trial Designed?
2
Treatment groups
Active Control
Placebo Group
Far-UVC light as an additional method of disinfection
"Inactive" fluorescent light (no additional disinfection)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Kenneth Rockwood
Lead Sponsor
Nova Scotia Health Authority
Collaborator
Department of Health, Nova Scotia
Collaborator
Research Nova Scotia
Collaborator
Citations
Far-UVC: Technology Update with an Untapped Potential ...
In the laboratory, 222 nm UVC is as effective a germicide as 254 nm GUV—including against Mycobacterium tuberculosis, SARS-CoV-2, and influenza ...
Far-UVC (222 nm) efficiently inactivates an airborne ...
Our data indicate that Far-UVC is likely to be more effective against common airborne viruses, including SARS-CoV-2, than bacteria and should ...
Far-UVC light (222 nm) efficiently inactivates clinically ...
Previous studies have shown that UVC radiation with a wavelength of 222 nm can effectively inactivate a wide range of microbial pathogens.
UVC Light for Airborne Epidemic Spread Prevention
UVC light disrupts the transcription and replication processes of microorganisms through photochemical reactions, rendering the pathogens unable ...
Germicidal UV Light and Incidence of Acute Respiratory ...
GUV light appliances have been shown to be highly effective in killing airborne viral pathogens, including influenza, tuberculosis, SARS-CoV-1, ...
Filter-Free, Harmless, and Single-Wavelength Far UV-C ...
In summary, our study suggests that far UV-C at 207 nm is an effective germicide while posing no harm to human cells. These results validate the ...
Far-UVC light (222 nm) efficiently and safely inactivates ...
Germicidal ultraviolet light, typically at 254 nm, is effective in this context but, used directly, can be a health hazard to skin and eyes. By ...
Assessing the safety of new germicidal far‐UVC technologies
Far-UVC light at 222 nm is showing significant potential to safely and efficiently inactivate airborne pathogens in occupied indoor locations.
Far-UVC light (222 nm) efficiently inactivates clinically ...
UVC blocks airborne and droplet-transmission respiratory tract viruses through space disinfection. UVC can efficiently disinfect viruses present ...
Far-UVC and Eye Safety: Findings from a 36-Month Study
222 nm Far-UVC proves safe for human eyes, even with long-term exposure. See how this technology transforms decontamination in hospitals and ...
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