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Lauric Acid and Berberine for Severe Infection (NUWISE Trial)

N/A

Recruiting

Research Sponsored by University of British Columbia

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

receiving enteral nutrition

Clinical diagnosis of Sepsis

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 28 days

Awards & highlights

NUWISE Trial Summary

This trial will test a supplement to see if it can raise cholesterol levels in ICU patients with severe infection. Patients will get usual care or supplement for 14 days, followed by phone calls at 28 and 90 days.

Eligible Conditions

Severe Infection

NUWISE Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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You are currently receiving nutrition through a feeding tube.

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You have been diagnosed with a severe infection called sepsis.

NUWISE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 28 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~28 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and 28 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Plasma HDL

Secondary outcome measures

28-day survival

Cytokine

WBC

NUWISE Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Lauric Acid and BerberineExperimental Treatment1 Intervention

Participants in this arm of the trial will receive 15 ml lauric acid and 1000 mg berberine daily (via feed tube) for the duration of time that they are receiving enteral feeding, up to a maximum time of 14 days

Group II: No-interventionActive Control1 Intervention

participants in this arm will receive no additional intervention, beyond standard of care

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of British ColumbiaLead Sponsor

1,413 Previous Clinical Trials

2,466,913 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To what extent is participant recruitment progressing for this experiment?

"Affirmative. The information on clinicaltrials.gov confirms that this trial is currently enrolling participants, which began being sought after on October 1st 2021 and was last updated on October 31st 2022. There are 48 available positions at a single site."

Answered by AI

Are there opportunities for volunteers to join this medical research?

"According to the information hosted on clinicialtrials.gov, this clinical trial is presently enrolling participants and has been since October 1st 2021; the listing was most recently updated on October 31st 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Nutritional Supplement for Patients With Severe Infection

john boyd 2021. "Nutritional Supplement for Patients With Severe Infection". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05602324.