DNA PCR vs Urine Culture for Urinary Tract Infection
What You Need to Know Before You Apply
What is the purpose of this trial?
Adults 18 years or older with urinary tract infection (UTI) symptoms. Participants will be assigned to either the urine culture group or the DNA PCR study group by randomization. At time of enrollment in the study they will be also asked to fill out two questionnaires. If prescribed antibiotics for treatment of a UTI, participants will then be called the day after they are scheduled to stop their antibiotics. Participants will be asked to fill out questionnaires the day after finishing antibiotics. Participants will be enrolled in the study for a maximum of 21 days.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot have taken antibiotics or phenazopyridine in the last 21 days to participate.
Is DNA PCR generally safe for diagnosing urinary tract infections?
How does DNA PCR treatment differ from other treatments for urinary tract infections?
DNA PCR (polymerase chain reaction) is a unique treatment for urinary tract infections because it uses molecular methods to identify bacteria directly from urine samples, unlike traditional urine cultures that may miss some infections. This approach can detect bacteria that are not identified by standard culture methods, potentially leading to more accurate and timely diagnosis.14678
What data supports the effectiveness of the treatment DNA Polymerase Chain Reaction for urinary tract infections?
Who Is on the Research Team?
David Sheyn, MD
Principal Investigator
University Hospitals
Are You a Good Fit for This Trial?
This trial is for adults over 18 with symptoms of a urinary tract infection (UTI). They must be willing to fill out questionnaires and can participate for up to 21 days. Specific inclusion or exclusion criteria are not provided.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are assigned to either the urine culture group or the DNA PCR study group and may be prescribed antibiotics for UTI treatment
Follow-up
Participants are monitored for symptom changes and asked to fill out questionnaires after completing antibiotics
What Are the Treatments Tested in This Trial?
Interventions
- DNA Polymerase Chain Reaction
Find a Clinic Near You
Who Is Running the Clinical Trial?
University Hospitals Cleveland Medical Center
Lead Sponsor