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Ketogenic Diet for Obesity Hypoventilation Syndrome (KETOHS Trial)

N/A
Waitlist Available
Led By Jonathan Jun, MD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up once every 2 weeks, over 4 weeks
Awards & highlights

KETOHS Trial Summary

This trial will test whether a ketogenic diet can improve breathing in people with obesity hypoventilation syndrome.

Eligible Conditions
  • Obesity Hypoventilation Syndrome
  • Ketogenic Diet
  • Hypercapnic Respiratory Failure

KETOHS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~once every 2 weeks, over 4 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and once every 2 weeks, over 4 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Awake venous carbon dioxide (PvCO2) Level
Secondary outcome measures
Change in Apnea Hypopnea Index
Change in Blood Pressure
Change in Body weight (kg)
+11 more

KETOHS Trial Design

1Treatment groups
Experimental Treatment
Group I: Ketogenic DietExperimental Treatment1 Intervention
Participants will receive the ketogenic diet.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ketogenic Diet
2016
Completed Phase 2
~460

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,259 Previous Clinical Trials
14,820,629 Total Patients Enrolled
Jonathan Jun, MDPrincipal InvestigatorJohns Hopkins University
3 Previous Clinical Trials
132 Total Patients Enrolled

Frequently Asked Questions

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~4 spots leftby Apr 2025