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Cold Condition for Hypothermia

N/A
Waitlist Available
Led By Gordon Giesbrecht, PhD
Research Sponsored by University of Manitoba
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 0, 20, 40, 60 and 90 minutes
Awards & highlights

Study Summary

This trial found that cooling the skin or core temperature causes reduced excitability in the corticospinal system, which may lead to shivering.

Eligible Conditions
  • Hypothermia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 0, 20, 40, 60 and 90 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and at 0, 20, 40, 60 and 90 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Corticospinal Excitability
Secondary outcome measures
Change in Core Temperature
Change in Metabolic Heat Production
Change in Skin Temperature
+1 more
Other outcome measures
Change in Maximal Voluntary Contraction of Elbow Flexors
Change in Peripheral nerve excitability

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Cold ConditionExperimental Treatment1 Intervention
Subjects will be cooled for 60-90 min at ~ 4-10°C using a liquid perfused suit. Subjects will then be rewarmed for 30 min at ~ 41°C using the liquid perfused suit.
Group II: Control ConditionActive Control1 Intervention
Subjects will sit at rest wearing a liquid perfused suit containing thermoneutral water for 60 min. The suit will not be turned on during this period.

Find a Location

Who is running the clinical trial?

University of ManitobaLead Sponsor
595 Previous Clinical Trials
199,512 Total Patients Enrolled
3 Trials studying Hypothermia
23 Patients Enrolled for Hypothermia
Gordon Giesbrecht, PhDPrincipal InvestigatorUniversity of Manitoba
2 Previous Clinical Trials
48 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Characterization of Corticospinal Excitability During Progressive Skin Cooling
Dr.Gordon Giesbrecht 2019. "Characterization of Corticospinal Excitability During Progressive Skin Cooling". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04253730.
~2 spots leftby Apr 2025
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