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Abdominal Strengthening Exercise for Parkinson's Disease

N/A
Waitlist Available
Led By Mandar Jog, MD
Research Sponsored by Faizan Ahmed
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 3 hours for each visit. a total of 2 visits are expected for each participant.
Awards & highlights

Study Summary

This trial is to study the effect of strengthening abdominal muscles in patients with Parkinson's Disease who have cardiovascular autonomic dysfunction.

Who is the study for?
This trial is for Parkinson's Disease patients aged 40-90, specifically those in stages 2 to 4 of the Hoehn and Yahr classification. It aims to help individuals who experience a sudden drop in blood pressure when changing postures, known as orthostatic hypotension.Check my eligibility
What is being tested?
The study tests if abdominal strengthening exercises can prevent blood pooling that causes dizziness or black-outs due to orthostatic hypotension. Participants will do these exercises at home for three months with follow-up testing.See study design
What are the potential side effects?
While not explicitly listed, potential side effects may include muscle soreness or strain from the abdominal exercises. As this is an exercise-based intervention, serious side effects are less likely compared to drug treatments.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 3 hours for each visit. a total of 2 visits are expected for each participant.
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 hours for each visit. a total of 2 visits are expected for each participant. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Blood Pressure
Secondary outcome measures
Changes in the ratio between oxy- and deoxy-hemoglobin
Composite Autonomic Severity Score
Dizziness Handicap Inventory score
+5 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Abdominal Strengthening ExerciseExperimental Treatment1 Intervention
All participants in this arm shall perform exercises for the strengthening of abdominal muscles for a period of three months in addition to the routine care provided to them for the management of Parkinson's Disease. The exercises are structured and need to be performed on a routine basis.
Group II: Routine CareActive Control1 Intervention
All participants in this group shall continue to obtain routine care for the management of Parkinson's Disease.

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Who is running the clinical trial?

Faizan AhmedLead Sponsor
Mandar Jog, MDPrincipal InvestigatorWestern University, London, ON
7 Previous Clinical Trials
174 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Biomedical Optics ExpressJournal
Improving the Depth Sensitivity of Time-resolved Measurements by Extracting the Distribution of Times-of-flight
Diop, Mamadou, and Keith St. Lawrence. 2013. “Improving the Depth Sensitivity of Time-resolved Measurements by Extracting the Distribution of Times-of-flight”. Biomedical Optics Express. The Optical Society. doi:10.1364/boe.4.000447.
Sports MedicineJournal
Heart Rate and Exercise Intensity During Sports Activities
Karvonen, Juha, and Timo Vuorimaa. 1988. “Heart Rate and Exercise Intensity During Sports Activities”. Sports Medicine. Springer Science and Business Media LLC. doi:10.2165/00007256-198805050-00002.
Journal of the Neurological SciencesJournal
Cardiovascular Autonomic Dysfunction in Parkinson's Disease
Ziemssen, Tjalf, and Heinz Reichmann. 2010. “Cardiovascular Autonomic Dysfunction in Parkinson's Disease”. Journal of the Neurological Sciences. Elsevier BV. doi:10.1016/j.jns.2009.08.031.
CirculationJournal
Guidelines for Clinical Exercise Testing Laboratories
Pina, Ileana L., Gary J. Balady, Peter Hanson, Arthur J. Labovitz, Deborah W. Madonna, and Jonathan Myers. 1995. “Guidelines for Clinical Exercise Testing Laboratories”. Circulation. Ovid Technologies (Wolters Kluwer Health). doi:10.1161/01.cir.91.3.912.
All > Orthostatic Hypotension > Parkinson
~41 spots leftby Apr 2025
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