Control wheat based cookies for High Blood Pressure (Hypertension)

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Chronic Disease Innovation Centre, Seven Oaks Hospital, Winnipeg, Canada
High Blood Pressure (Hypertension)+1 More
Control wheat based cookies - Other
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether oats containing high molecular weight β-glucan can reduce blood pressure.

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Eligible Conditions

  • High Blood Pressure (Hypertension)

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Control wheat based cookies will improve 1 primary outcome, 4 secondary outcomes, and 1 other outcome in patients with High Blood Pressure (Hypertension). Measurement will happen over the course of Day 1 and day 28 of each study period.

Day 28
Body weight
Waist circumference
Day 26
Mean systolic blood pressure
Day 26
Dietary fibre by 24 hour recall
Mean arterial blood pressure
Mean diastolic blood pressure

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Study period 1: β-glucan Oat ; Study period 2: Wheat
1 of 2
Study period 1: Wheat ; Study period 2: β-glucan Oat
1 of 2
Experimental Treatment

This trial requires 24 total participants across 2 different treatment groups

This trial involves 2 different treatments. Control Wheat Based Cookies is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Study period 1: β-glucan Oat ; Study period 2: WheatFor the first period, the participant will receive food products made from oats containing a total of 4 grams per day HMW oat β-glucan. For the second period, the participant will receive food products made from wheat.
Study period 1: Wheat ; Study period 2: β-glucan OatFor the first period, the participant will receive food products made from wheat. For the second period, the participant will receive food products made from oats containing a total of 4 grams per day HMW oat β-glucan.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: day 1, 2, and 3 and day 26, 27, and 28 of each study period
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly day 1, 2, and 3 and day 26, 27, and 28 of each study period for reporting.

Closest Location

Chronic Disease Innovation Centre, Seven Oaks Hospital - Winnipeg, Canada

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 6 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
A person with a body mass index of 20-35 kg/m2 is considered overweight. show original
were significantly reduced (−7.8mm Hg and −4.4mm Hg, respectively) after consuming the odd dietary pattern for two weeks show original
The participant is willing and able to give consent for participation in the trial show original
The target population generally consists of healthy males and females aged between 40 and 75 who are not pregnant or lactating. show original
The text is saying that the person is willing to comply with the protocol requirements. show original
, they were randomly split into two groups The participants were willing to maintain their current weight and activity level throughout the study and they were randomly split into two groups. show original

Patient Q&A Section

Can hypertension be cured?

"Results from a recent clinical trial suggest that hypertensive individuals tend to develop other chronic health problems from their initial hypertension. If more rigorous efforts are made to prevent hypertension, however, it might be possible for a subgroup of individuals to limit the occurrence of subsequent chronic diseases and a subsequent reduction in their blood pressure." - Anonymous Online Contributor

Unverified Answer

What causes hypertension?

"We know that sodium intake has been found to be the most important cause of hypertension in a population all over the world. Findings from a recent study, in addition, we know that potassium intake is negligible with respect to sodium intake and, indeed, has been found to be lower in black people than in white people. Now, we shall start to speak about one of the causes of hypertension. Diabetes mellitus answer: Diabetes mellitus is a cause of hypertension, as it is a cause for high consumption of simple sugars. In the second place, it has been seen that the blood sugar level is significantly elevated with the onset of diabetes mellitus." - Anonymous Online Contributor

Unverified Answer

What are the signs of hypertension?

"The most common signs associated with hypertension include palpitations in patients between 40 and 60 years of age, and high blood pressure at presentation. Younger hypertensive patients typically present more rapidly." - Anonymous Online Contributor

Unverified Answer

How many people get hypertension a year in the United States?

"Results from a recent clinical trial has shown a substantial increase in the incidence of hypertension in the U.S. population over a five-year period. The rate of hypertension increased by 37% and mean blood pressure increases by 37% as a result of the study subjects' average age being younger. However, these findings are not conclusive because of their cross-sectional format and this would need to be further assessed with longitudinal cohort data." - Anonymous Online Contributor

Unverified Answer

What are common treatments for hypertension?

"Common treatments for hypertension are medications to control blood pressure, blood pressure-reducing lifestyle modification such as diet modification, exercise, weight loss and maintenance, and a variety of other lifestyle modifications. Common treatments for hypertension may also include blood pressure monitoring, drug regimen modification, and referral to specialty hypertension services. Treatments with antihypertensive agents and drugs to treat anemia are often associated with antihypertensive drugs and lifestyle modifications. Some medications, such as ACE inhibitors, ACE inhibitors with angiotensin receptor blockers, calcium channel blockers, nifedipine, or diuretics may be used as antihypertensive agents. Lifestyle modifications that lower blood pressure with reduced sodium intake can help manage hypertension." - Anonymous Online Contributor

Unverified Answer

What is hypertension?

"Hypertension is defined as a high blood pressure, no matter what the cause. The American Heart Association defines hypertension as a blood pressure of 130/80 or higher. More specific definition methods include the use of ambulatory blood pressure measurements, multiple arterial blood gas test, echocardiography, or radimod. To avoid misdiagnosis or ineffective therapy, patients with hypertension should be evaluated and treated according to the risks and benefits of treatment." - Anonymous Online Contributor

Unverified Answer

What are the common side effects of control wheat based cookies?

"The most common adverse effects of consumption of wheat based cookies are headache and constipation. Both of these symptoms can be very debilitating as they effect their daily lives. If you would like to find more on this, see the full article on https://www.thedoctorsite.com/pages/viewtopic.asp?id=1556" - Anonymous Online Contributor

Unverified Answer

Does hypertension run in families?

"Findings from a recent study concluded that more than one parent had hypertension in two out of three families in which hypertension could be related to familial inheritance of HTN. The risk to have parents positive for HTN might be as high as 2.27 for 1 sibling positive for a single parent of HTN." - Anonymous Online Contributor

Unverified Answer

What does control wheat based cookies usually treat?

"There are no trials that can prove the superiority of wheat cookies over other types of biscuits. Moreover, there is no reliable evidence to prove that using wheat based cookies will help controlling blood pressure. Therefore, the recommendation of wheat based cookies is based on anecdotal evidence in terms of clinical practice in general." - Anonymous Online Contributor

Unverified Answer

Is control wheat based cookies typically used in combination with any other treatments?

"There are significant patient perceptions of wheat based biscuits as part of care, and there is a trend towards the use of biscuits in lieu of wheat and sugar based biscuits." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets hypertension?

"The age of people with hypertension has been reported to be 30 to 50 years in most research; however, recent observations have suggested that, in some countries, the mean age at onset is earlier than previously reported. It appears there is a strong desire to diagnose hypertension as soon as possible, but this is obviously not a real obstacle when considering the health consequences of untreated hypertension." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in control wheat based cookies for therapeutic use?

"The new generation of cookies for therapeutic use have the ability to regulate blood pressure via the antihypertensive effects of the polyphenols in the wheat flour cake." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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