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Exercise for High Blood Pressure
N/A
Recruiting
Led By Michael Koehle, MD, PhD
Research Sponsored by University of British Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up continuously throughout the 30 minute exercise bouts (during exposure)
Awards & highlights
Study Summary
This trial is investigating if traffic-related air pollution has an effect on cardiovascular and pulmonary response to exercise in patients with hypertension.
Eligible Conditions
- High Blood Pressure
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ continuously throughout the 30 minute exercise bouts (during exposure)
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~continuously throughout the 30 minute exercise bouts (during exposure)
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change from Baseline Blood Pressure at 2 Hours Post-Exposure
Secondary outcome measures
24-Hour Blood Pressure
Change from Baseline Arterial Stiffness at 2 Hours Post-Exposure
Change from Baseline FEF25-75 and PEFR at 2 Hours Post-Exposure
+6 moreTrial Design
2Treatment groups
Experimental Treatment
Group I: Low traffic-related air pollutionExperimental Treatment1 Intervention
Participants will exercise in an environment with low levels of traffic-related air pollution first. Afterwards, participants will complete the same exercise in an environment with high levels of traffic-related air pollution.
Group II: High traffic-related air pollution firstExperimental Treatment1 Intervention
Participants will exercise in an environment with high levels of traffic-related air pollution first. Afterwards, participants will complete the same exercise in an environment with low levels of traffic-related air pollution.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Exercise
2016
Completed Phase 1
~760
Find a Location
Who is running the clinical trial?
University of British ColumbiaLead Sponsor
1,413 Previous Clinical Trials
2,466,931 Total Patients Enrolled
Michael Koehle, MD, PhDPrincipal InvestigatorProfessor
3 Previous Clinical Trials
53 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You are taking medication for high blood pressure or heart problems called beta-blockers or ARBs.You are currently taking hormone replacement therapy.You have been diagnosed with any heart or lung conditions or diseases, besides high blood pressure.You have an injury or limitation in your legs that prevents you from safely engaging in moderate-intensity exercise.You live with someone who currently smokes cigarettes, e-cigarettes (vaping), or cannabis.You are taking certain over-the-counter medicines or supplements that may affect your heart health, based on the decision of the study leader.
Research Study Groups:
This trial has the following groups:- Group 1: High traffic-related air pollution first
- Group 2: Low traffic-related air pollution
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
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