← Back to Search

High dietary sodium intake for High Blood Pressure (MEASURE Trial)

N/A

Recruiting

Led By Cheryl A Anderson, PhD

Research Sponsored by University of California, San Diego

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Willing to eat all meals provided by the study for two 14-day feeding periods

At least 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 60 days

Awards & highlights

MEASURE Trial Summary

This trial will test the effects of high and low dietary sodium intake on the body's storage and excretion of sodium. Results could help manage hypertension and related conditions.

Who is the study for?

This study is for adults aged 18-69 with high blood pressure, who are on no more than one medication for it. Participants must have a primary care provider and be willing to eat only the meals provided by the study for 50 days.Check my eligibility

What is being tested?

The trial is exploring how different levels of dietary sodium intake (high vs. low) affect the body's handling of sodium in terms of storage and excretion, and its impact on blood pressure in a diverse group of adults.See study design

What are the potential side effects?

While not explicitly listed, potential side effects may include changes in blood pressure or fluid balance due to varying sodium intake levels which could lead to symptoms like dizziness, swelling, or changes in urination.

MEASURE Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am willing to eat only the meals provided by the study for two weeks.

Select...

I am 18 years old or older.

Select...

I take two or fewer medications for high blood pressure.

Select...

I have been diagnosed with high blood pressure or pre-hypertension.

MEASURE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 60 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~60 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and 60 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Blood pressure

Concentration of sodium, potassium, and hormone regulators in excreted urine

Estimated sodium concentration in bone

+1 more

Secondary outcome measures

Racial differences in concentration of urinary potassium excretion

Bone and Bones

MEASURE Trial Design

2Treatment groups

Experimental Treatment

Group I: Low-high dietary sodiumExperimental Treatment2 Interventions

Low sodium diet (2300 mg/day) feeding period followed by high sodium diet (3400 mg/day) feeding period

Group II: High-low dietary sodiumExperimental Treatment2 Interventions

High sodium diet (3400 mg/day) feeding period followed by low sodium diet (2300 mg/day) feeding period

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of California, San DiegoLead Sponsor

1,121 Previous Clinical Trials

1,520,874 Total Patients Enrolled

Cheryl A Anderson, PhDPrincipal InvestigatorUniversity of California, San Diego

1 Previous Clinical Trials

55 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new participants still able to enroll in this clinical trial?

"According to clinicaltrials.gov, this medical investigation is actively recruiting participants. The trial was initially shared on November 10th 2021 and has since been modified on December 3rd 2021."

Answered by AI

Does this trial encompass those aged 85 and younger?

"This medical study is open to adults between 18 and 69 years old. There are 54 trials recruiting underage children, and 661 studies for elderly patients aged 65 or higher."

Answered by AI

Who would qualify to participate in this experiment?

"This medical research is seeking 50 volunteers, aged between 18 and 69 years-old who are suffering from hypertension. Aside from this requirement, participants must be willing to consume all meals provided by the study for a period of two months, while taking no more than one medication for high blood pressure during that time."

Answered by AI

What is the capacity of this research project with regard to participants?

"Affirmative. Clinicaltrials.gov states that this clinical trial, which was originally advertised on November 10th 2021, is currently recruiting participants in need of the proposed intervention. There are 50 vacancies at a single medical centre."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Human Sodium Balance Study

Cheryl Anderson 2021. "Human Sodium Balance Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04110262.

All > Hypertension