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Intradialytic Blood Pressure Slope Based Ultrafiltration for Renal Disease (IBPS Trial)

N/A
Waitlist Available
Led By Peter Van Buren, MD, MSCS
Research Sponsored by University of Texas Southwestern Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 4 months
Awards & highlights

IBPS Trial Summary

This trial is testing a new method of ultrafiltration for dialysis patients, which may be more effective than the standard method. The trial includes a cross sectional component to study the associations between intradialytic blood pressure slopes and measurements of extracellular water/body weight.

Eligible Conditions
  • Renal Disease
  • Fluid Imbalance
  • High Blood Pressure

IBPS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 4 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 4 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Mean Ambulatory Systolic Blood Pressure
Secondary outcome measures
Change in Extracellular Volume/Body Weight Ratio

IBPS Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: IBPS GroupExperimental Treatment1 Intervention
This group will have ultrafiltration prescriptions dictated by a pre-specified protocol that is based on monthly assessment of intradialytic blood pressure slopes obtained over a two week period.
Group II: Standard CareActive Control1 Intervention
This arm of subjects will have all aspects of fluid management and dialysis management managed by the his/her individual nephrologist

Find a Location

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor
1,048 Previous Clinical Trials
1,053,761 Total Patients Enrolled
Peter Van Buren, MD, MSCSPrincipal Investigator - University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Using Intradialytic Blood Pressure Slopes to Guide Ultrafiltration
Peter Van Buren 2017. "Using Intradialytic Blood Pressure Slopes to Guide Ultrafiltration". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03303391.
~2 spots leftby Apr 2025
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