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Generic Cardiovascular Medications

receipt of free generic samples for High Cholesterol (SAMPLES Trial)

N/A
Waitlist Available
Led By William H Shrank, MD
Research Sponsored by Brigham and Women's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Primary care physicians receiving an existing academic detailing program in Pennsylvania
Timeline
Screening 3 weeks
Treatment Varies
Follow Up the year before and the year after provision of samples
Awards & highlights

SAMPLES Trial Summary

In this randomized controlled trial, we will provide primary care physicians with free samples of highly effective generic cardiovascular medications. We will test whether this intervention will stimulate cost-effective prescribing, reducing drug costs and improving adherence to essential cardiovascular medications.

Eligible Conditions
  • High Cholesterol
  • High Blood Pressure

SAMPLES Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

SAMPLES Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~in the year subsequent to patient initiation of an anti-hypertensive or lipid-lowering medication
This trial's timeline: 3 weeks for screening, Varies for treatment, and in the year subsequent to patient initiation of an anti-hypertensive or lipid-lowering medication for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Patient adherence - Amount of prescriptions actually filled (Proportion of Days Covered) within each class in the first year of use of an anti-hypertensive or lipid-lowering medication
Percentage of prescriptions filled for generic medications
Secondary outcome measures
Guideline adherence - Proportion of patients who received first-line anti-hypertensive medications suggested by JNC-VII when medications are initiated.
The sum of medication costs for all prescriptions used to treat either hypertension or hypercholesterolemia.

SAMPLES Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: receipt of free generic samplesExperimental Treatment1 Intervention
Group II: usual prescribingActive Control1 Intervention

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Who is running the clinical trial?

Brigham and Women's HospitalLead Sponsor
1,609 Previous Clinical Trials
11,469,667 Total Patients Enrolled
William H Shrank, MDPrincipal InvestigatorBrigham and Women's Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
The Effect of Providing Free Samples of Generic Cardiovascular Medications to Physicians
2010. "The Effect of Providing Free Samples of Generic Cardiovascular Medications to Physicians". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00761904.
All > Cardiovascular
~46 spots leftby Apr 2025
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