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CREST for Hoarding Disorder (CREST Trial)

N/A
Waitlist Available
Led By Catherine R Ayers, PhD
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights

CREST Trial Summary

This trial will study a new treatment for hoarding disorder that considers age and cognitive function. The goal is to learn how well the treatment works and what long-term effects it has.

CREST Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Saving Inventory Revised
Secondary outcome measures
Specific Levels of Functioning test (SLOF)
UCSD Performance-Based Skills Assessment (UPSA)
UCSD SORT Test

CREST Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: CRESTExperimental Treatment1 Intervention
Compensatory Cognitive Training (CCT) is a manualized, low-tech, cognitive training intervention designed to target cognitive impairments common in people with psychiatric illness. The CCT modules specifically selected for CREST map onto known areas of HD neurocognitive deficits or weakness and include training in prospective memory, prioritizing, problem solving, planning, and cognitive flexibility. Symptoms of acquiring and saving are themselves avoidance behaviors that are performed to avoid internal distress related to negative thoughts and emotions. Avoidance serves to reduce distress related to the beliefs regarding the necessity and utility of possessions. In the CREST condition, the second part and the majority of treatment is dedicated to exposure therapy (ET) for discarding and not acquiring while in the control condition, the entire treatment will consist of ET.
Group II: ETActive Control1 Intervention
The investigators propose to use a robust control condition, ET, with the same frequency and amount of therapist contact as CREST. Twenty-six weekly, individual ET sessions (6 months) will be delivered. The control group will receive ET for all 26 sessions and no cognitive training. As in CREST, the ET sessions will be manualized and copies utilized during session by both the patient and therapist.

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Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,609 Previous Clinical Trials
3,306,318 Total Patients Enrolled
1 Trials studying Hoarding Disorder
130 Patients Enrolled for Hoarding Disorder
Catherine R Ayers, PhDPrincipal InvestigatorVA San Diego Healthcare System, San Diego, CA
3 Previous Clinical Trials
324 Total Patients Enrolled
1 Trials studying Hoarding Disorder
130 Patients Enrolled for Hoarding Disorder

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there certain requirements that must be met to join this research project?

"115 participants, aged from 18 to 85 years old and diagnosed with hoarding disorder are needed for this experiment. In addition, eligible individuals must be veterans within the same age range, stable on medications for at least 12 weeks before enrolment, with no changes in pharmaceuticals expected during the year-long study period. Finally, volunteers need to consent of their own volition to partake in this trial."

Answered by AI

Are younger people within the age range of eligibility for this clinical research?

"As indicated in the enrollment requirements, only those aged 18-85 are eligible to partake in this clinical trial."

Answered by AI

Is this research currently open to fresh participants?

"Contrary to what is indicated on clinicaltrials.gov, this particular trial is no longer recruiting patients having been first posted October 1st of 2015 and last updated November 18th 2022. Despite this, there are 11 other studies actively seeking participants at the moment."

Answered by AI

Who else is applying?

What state do they live in?
Massachusetts
How old are they?
18 - 65
What portion of applicants met pre-screening criteria?
Did not meet criteria
Recent research and studies
clinicaltrials.govStudy
Cognitive Rehab and Exposure Treatment for Hoarding
2015. "Cognitive Rehab and Exposure Treatment for Hoarding". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02402647.
~12 spots leftby Apr 2025
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