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Genetic testing for Castleman's Disease

N/A

Waitlist Available

Led By Sudipto Mukherjee, MD, PhD

Research Sponsored by Case Comprehensive Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 12 months from last participant accrued

Awards & highlights

Study Summary

This trial will use WES to learn more about rare blood diseases and identify possible treatments.

Eligible Conditions

Castleman's Disease
Langerhans Cell Histiocytosis
Non-Langerhans-Cell Histiocytosis

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 12 months from last participant accrued

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 12 months from last participant accrued

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 12 months from last participant accrued for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Proportion of genomic analyses yielding genetic aberrations

Secondary outcome measures

Completion rates of genetic counseling for germline mutations

Proportion of genomic analyses yielding actionable genetic aberrations

Proportion of genomic analyses yielding germline genetic aberrations

+1 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Genomic analysisExperimental Treatment1 Intervention

When a participant's disorder was diagnosed, blood or tissue specimen was collected. A part of the tissue or blood will be sent to an outside company, Tempus, to be tested for specific genetic changes and the results will be sent back to participants' physician.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Genetic testing

2017

N/A

~5890

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Case Comprehensive Cancer CenterLead Sponsor

452 Previous Clinical Trials

31,775 Total Patients Enrolled

Sudipto Mukherjee, MD, PhDPrincipal InvestigatorCleveland Clinic, Case Comprehensive Cancer Center

3 Previous Clinical Trials

74 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the capacity of this clinical experiment?

"Affirmative. According to clinicaltrials.gov, this scientific trial is actively enrolling participants after being posted on June 18th 2021 and last updated on June 21st 2022. The research necessitates 135 volunteers from a single location."

Answered by AI

Are there still vacancies in this clinical investigation?

"On clinicaltrials.gov, this medical trial is listed as actively recruiting patients. The post was initially uploaded on June 18th 2021 and most recently revised on June 21st 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease

2021. "Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05028621.