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Chiropractic Spinal Manipulative Therapy for Sciatica

N/A
Waitlist Available
Led By Paul B Bishop, DC, MD, PhD
Research Sponsored by Vancouver General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up the number of patients recruited per week for 19 months
Awards & highlights

Study Summary

Comparisons of surgical and non-operative treatment of patients with acute sciatica secondary to lumbar intervertebral disc herniation (AS/LDH) have shown no appreciable difference in outcome. The composition of the non-operative treatment of this patient population remains poorly defined. Spinal manipulative therapy (SMT) has demonstrated value in the treatment of AS/LDH. Recent preliminary studies suggest that SMT provides therapeutic benefit through the modulation of in vivo inflammatory mediators. This feasibility study will define the key experimental variables required to conduct a large multicentre study that will clarify the biological and clinical outcomes of SMT in the treatment of patients with AS/LDH.

Eligible Conditions
  • Sciatica
  • Slipped Disc

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~the number of patients recruited per week for 19 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and the number of patients recruited per week for 19 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Rate of recruitment of eligible patients
Secondary outcome measures
Cytokine and cytokine mRNA levels in serum
Cytokine and cytokine mRNA levels in serum.
Modified Roland Disability Questionnaire (mRDQ) score and Visual Analogue Scale (VAS) pain scale.
+3 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Usual CareExperimental Treatment1 Intervention
Group II: Chiropractic Spinal Manipulative TherapyExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

Vancouver General HospitalLead Sponsor
40 Previous Clinical Trials
19,575 Total Patients Enrolled
Paul B Bishop, DC, MD, PhDPrincipal InvestigatorClinical Associate Professor, I.C.O.R.D. Research Professor, Division of Spine, Department of Orthopaedics, University of British Columbia

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Chiropractic Spinal Manipulative Therapy for Acute Sciatica Secondary to Lumbar Disc Herniation
Dr. Paul Bishop 2012. "Chiropractic Spinal Manipulative Therapy for Acute Sciatica Secondary to Lumbar Disc Herniation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01552486.
All > Hernia
~3 spots leftby Apr 2025
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