Treatment for Hemorrhage

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
BC Children's Hospital - Department of Anesthesia, Vancouver, Canada
Hemorrhage+1 More
Eligibility
Any Age
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a new device can be used to isolate the lungs during intubation.

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Eligible Conditions

  • Hemorrhage
  • Pulmonary Haemorrhage

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome and 3 secondary outcomes in patients with Hemorrhage. Measurement will happen over the course of At the end of the trial, within an hour of starting the first practice intubation..

At the end of the trial, within an hour of starting the first practice intubation.
Model utility
Within 10 minutes from start of direct laryngoscopy
Time to successful intubation
Total time to successful lung isolation.
Within 10 minutes from successful intubation
Time to successful method placement

Trial Safety

Safety Estimate

1 of 3

Trial Design

0 Treatment Group

This trial requires 20 total participants across 0 different treatment group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: within 10 minutes from successful intubation
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly within 10 minutes from successful intubation for reporting.

Who is running the study

Principal Investigator
F. R. P.
F. Robert Purdy, Principle Investigator
University of British Columbia

Closest Location

BC Children's Hospital - Department of Anesthesia - Vancouver, Canada

Eligibility Criteria

This trial is for patients born any sex of any age. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Anesthesia fellows
Practicing anesthesiologists

Patient Q&A Section

What is the average age someone gets hemorrhage?

"The age of hemorrhaged patient was 63.6 with the male:female ratio being 50% higher than that of hemorrhagic stroke cohort. The mean age and gender for both groups was 64.5 and 81, respectively." - Anonymous Online Contributor

Unverified Answer

How does treatment work?

"There was a significant reduction of hemoglobin levels, but these parameters did not change after treatment. Hemoglobin concentrations in the study group were lower than those in the control group at baseline. The use of low-molecular-weight heparin or anticoagulation was the only independent factor of lowering hemoglobin concentration. Low-molecular-weight heparin does not seem to have effect on hematocrit or hemoglobin level." - Anonymous Online Contributor

Unverified Answer

What are the signs of hemorrhage?

"Bleeding is the major cause of death and morbidity in women in the first half of pregnancy. Preeclamptic heart disease, uncontrolled hypertension, and antiphospholipid syndrome are the most common cause of preeclampsia. Although the most common causes of death in pregnancy are related to complications before birth, the exact cause of infant mortality is poorly understood." - Anonymous Online Contributor

Unverified Answer

What is hemorrhage?

"Hemorrhage is the loss of blood into an external cavity in animals, such as a joint in a joint. Hemorrhagic conditions such as hypovolemic shock, shock, shock, ischemic, or post-mortem shock all can affect the internal environment of the body.\n\n- "Human Physiology" Online Video at the University of Illinois at Chicago"

"Myrsine hoffmannsis\n\nMyrsine hoffmannsis is a species of plant in the family Primulaceae." - Anonymous Online Contributor

Unverified Answer

What are common treatments for hemorrhage?

"In terms of treatment of both stable and unstable patients, there is no standard of care. The treatments are based on medical history, physical exam and assessment of patients by trauma surgeons. A consensus guideline with guidelines as to what to do with patients in trauma is lacking. There is no consensus on the best method of diagnosing, prognosticating and treating hemorrhage patients. The guidelines of the treatment of hemorrhage in both stable and unstable patients remain unclear. The management of children with bleeding disorders remains unclear. The management of elderly patients is complicated with low blood pressure, renal and hepatic dysfunction. Advanced trauma life support guidelines emphasize a non-directed approach to treating trauma patients." - Anonymous Online Contributor

Unverified Answer

How many people get hemorrhage a year in the United States?

"About 4 to 10% of patients experience some form of hemorrhagic event during the year, and about 500,000 patients experience a catastrophic event every year, corresponding to about 8% of patients." - Anonymous Online Contributor

Unverified Answer

Can hemorrhage be cured?

"Hemorrhage can be a challenging condition to manage because of its complexity. However, many causes of hemorrhage can be cured with a number of simple strategies. As many hemorrhages can be prevented or reduced by these simple strategies, it is worthwhile to consider these strategies, especially for patients who have not been cured or whose treatment has been stopped because of bleeding." - Anonymous Online Contributor

Unverified Answer

What causes hemorrhage?

"There is good evidence that the risk of hemorrhage increases with age and smoking. There is also strong evidence that high levels of alcohol consumption increase the risk of hemorrhage." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving treatment?

"Patients undergoing liver transplantation often experience nausea and vomiting. Fewer than half of patients in the study reported nausea and vomiting during the day before transplant, but one half of the group reported nausea and vomiting one month after surgery. The incidence of nausea and vomiting decreased from baseline to post-operative day 4 but began to rise again at 7 days. In a multivariate analysis, patient distress scores and preoperative drug doses of antiemetic medications significantly predicted nausea and vomiting, with post-operative day 4 scores being the strongest predictors." - Anonymous Online Contributor

Unverified Answer

How serious can hemorrhage be?

"The mortality associated with acute hemorrhage is not always understood to the full extent. This is in part because of uncertainty about the role of blood transfusion, in part because of confusion caused by the term 'emergency,' and in part because of the lack of clear evidence to support the conclusions that are drawn. The value of blood transfusion in life-threatening hemorrhage is not clear." - Anonymous Online Contributor

Unverified Answer

Does hemorrhage run in families?

"This large, multiethnic sample of Caucasian patients with hemostatic problems and a history of a bleeding tendency shows a higher risk of hemorrhage in family members. Clinicians should keep the possibility of hemostatic disorder in the differential diagnosis of patients with unexplained hematuria and/or iron-deficiency anemia." - Anonymous Online Contributor

Unverified Answer

What is the latest research for hemorrhage?

"In patients with hemorrhage, there is still no consensus about treatment guidelines. Hemorrhage should be treated with multimodal treatment, in which patients are carefully monitored for complications and complications are avoided through careful management. However, in order to find a low incidence of hemorrhage complications, it is very important to educate and inform the patients. Furthermore, blood transfusion should be avoided, especially in patients with a low hemoglobin level. In those patients, we should consider the need for a timely blood transfusion. The last point of this paper is that we should educate about hemorrhage, which can greatly affect outcome and quality of life." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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