Virtual Reality (A) then Task (B) for Hemiplegia

Phase-Based Estimates
1
Effectiveness
1
Safety
Nancy L Devine, Pocatello, ID
+5 More
Virtual Reality (A) then Task (B) - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Hemiplegia

Study Summary

This study is evaluating whether a virtual reality intervention may help improve arm function for individuals with one arm that does not function well due to a stroke, head injury, or cerebral palsy.

See full description

Eligible Conditions

  • Hemiplegia
  • Cerebral Palsy
  • Paresis
  • Hemiplegic Cerebral Palsy
  • Upper Extremity Paresis
  • Hemiplegia and/or Hemiparesis Following Stroke

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Compared to trials

Study Objectives

This trial is evaluating whether Virtual Reality (A) then Task (B) will improve 3 primary outcomes and 2 secondary outcomes in patients with Hemiplegia. Measurement will happen over the course of 12 weeks.

12 weeks
Semi-structured interview
Week 12
Change in Active and Passive Range of Motion
Change in Box & Block Test
Change in Fugl-Meyer Assessment (UE portion)
Change in Stroke Impact Scale 3.0

Trial Safety

Safety Estimate

1 of 3

Compared to trials

Trial Design

2 Treatment Groups

No Control Group
Sequence #1

This trial requires 15 total participants across 2 different treatment groups

This trial involves 2 different treatments. Virtual Reality (A) Then Task (B) is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Sequence #1
Behavioral
Participants will receive nine 30 minute sessions (over 3 weeks) of intervention A followed by nine 30 minute sessions (over 3 weeks) of intervention B.
Sequence #2
Behavioral
Participants will receive nine 30 minute sessions (over 3 weeks) of intervention B followed by nine 30 minute sessions (over 3 weeks) of intervention B.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1st week, 4 weeks, 8 weeks, 12 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 1st week, 4 weeks, 8 weeks, 12 weeks for reporting.

Closest Location

Nancy L Devine - Pocatello, ID

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
18 - 89 years old
One arm not fully functional due to a stroke, brain injury, or cerebral palsy
More than 1 year since neurologic even that impaired arm function

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes hemiplegia?

Add answer

About 20% of cases of hemiplegia are familial and autosomal dominant in origin. The remaining are acquired or idiopathic. Some acquired cases may be caused by strokes or some other damage or disruption of the blood–brain barrier after brain injury. All of these cases have a similar underlying problem where blood vessels are damaged or blocked at the site of a lesion of the brain. The damaged blood vessels do not permit blood to reach the brain tissue. Brain tissue is then starved.

Unverified Answer

Can hemiplegia be cured?

Add answer

Hemiplegic children with severe disabling physical disabilities may benefit from a multidisciplinary rehabilitation program and home-based physical exercises to regain control of their spastic and achilles muscles.

Unverified Answer

What is hemiplegia?

Add answer

Hemiplegia is paralysis or weakness to one side of the body, most often caused by vascular disease. Approximately 1% of the US population is currently diagnosed with hemiplegia.

Unverified Answer

What are the signs of hemiplegia?

Add answer

[Hemiplegia] presents with a high rate of sensory deficits and proprioceptive dysfunction, which can lead to difficulty with balance, walking, and other non-domestic activities. Clinically, you may have signs of a decreased level of consciousness, such as slurred speech. [Hemiplegia’s] effects can diminish over time, but [hempilegia’s] effects are permanent. It is important to be aware of your symptoms and report them to your doctor as soon as possible.

Unverified Answer

What are common treatments for hemiplegia?

Add answer

Treatment for hemiplegia usually involves medication, braces, or a combination of these treatments. Exercise and physical therapy are also commonly used treatments of hemiplegia. Rehabilitation may also be used for a variety of different movement disorders. There is not enough data to provide an exact list of treatment options. However, there are two important factors that can affect how effective certain treatments for hemiplegia may be, namely if you have a traumatic insult or if you have a stroke. [With Treatment options, please see the section with Hemiplegia Treatment]\nhttps://www.neurologydiagnostics.

Unverified Answer

How many people get hemiplegia a year in the United States?

Add answer

A total of 2.4 million people in the United States will have at least one type of hemiplegia in 2007. Almost half (47%) of these will get hemiplegia due to stroke.

Unverified Answer

How does virtual reality (a) then task (b) work?

Add answer

In this exploratory study, we were successful in creating a task that allows participants to be in VR to complete in order to gain as much information as possible and then analyze their ability to perform the task in order to learn more about the participants and the task. Using the VR test, we were able to show that some participants, while being in VR, have difficulty completing this task. Most of the participants that had VR experience had more difficulty completing the task and were more likely to make a mistake than those who weren't VR experienced.

Unverified Answer

How serious can hemiplegia be?

Add answer

Patients with severe hemiplegia who do not receive intensive training have the highest complication rate and longest hospital stay. Patients with severe hemiplegia and mild or no deficits have a low risk of complications and can be discharged home after a brief period. Intensive rehabilitation that incorporates principles of neurorehabilitation ensures that hemiplegic patients can become as independent as possible.

Unverified Answer

What is the primary cause of hemiplegia?

Add answer

The cause of hemiplegia is not always directly linked to cerebrovascular accidents. It is important to take this into account when diagnosing this disorder and to evaluate the individual's prognosis. The underlying mechanism of hemiplegia is not fully understood, but there are some theories (e.g., [lack of nerve transmission signals due to inadequate myelination in myelinated nerve fibers with a low velocity]) that are being tested. A variety of techniques are being used to search for the underlying mechanism of this disease. Clinical trials (e.g., [Tonic Pincer Maneuver]; https://www.researchgate.

Unverified Answer

What is the latest research for hemiplegia?

Add answer

The clinical application of these results will depend on the effectiveness of these treatments. The ultimate goal is to reduce disabling symptoms, to prevent or slow the aging process, and to improve the quality of life of patients.

Unverified Answer

Have there been any new discoveries for treating hemiplegia?

Add answer

No conclusive research has been found, although it is reported that the research regarding the treatment of posttraumatic hemiplegia shows some new treatments have been developed.

Unverified Answer

What are the common side effects of virtual reality (a) then task (b)?

Add answer

Findings from a recent study indicate that VR may result in a temporary impairment in psychomotor skills, which may not be compensated for a week after the VR simulation. However, this did not translate into functional impairment in real life.

Unverified Answer
See if you qualify for this trial
Get access to this novel treatment for Hemiplegia by sharing your contact details with the study coordinator.