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Light Therapy

Bright White Light (BWL) Litebook for Heart Failure (Light-Heart Trial)

N/A
Waitlist Available
Led By Jeanne Maglione, MD, PhD
Research Sponsored by University of California, San Diego
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and at 8 week
Awards & highlights

Light-Heart Trial Summary

The Light-Heart study is a randomized, double-blind, controlled trial investigating the effects of bright white light (BWL) therapy on depressive symptoms, quality of life, and functioning in patients with Stage B heart failure. The study is a randomized, double-blind, controlled trial of 8 weeks of morning BWL therapy compared with morning dim red light (DRL) treatment in older (60 years or older) 122 Stage B (early, asymptomatic) HF patients.

Eligible Conditions
  • Heart Failure
  • Depression

Light-Heart Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and at 8 week
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and at 8 week for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in depressive symptoms will be assessed with the Beck Depression Inventory.
Secondary outcome measures
The Short Form (SF)-36 questionnaire will be used to assess QOL and subjective functioning.

Light-Heart Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Bright White Light (BWL) LitebookExperimental Treatment1 Intervention
Participants will be instructed to use the BWL Litebook for an hour every day for 8 weeks.
Group II: Dim Red Light (DRL) LitebookPlacebo Group1 Intervention
Participants will be instructed to use the DRL (comparison condition) Litebook for an hour every day for 8 weeks.

Find a Location

Who is running the clinical trial?

University of California, San DiegoLead Sponsor
1,120 Previous Clinical Trials
1,521,285 Total Patients Enrolled
13 Trials studying Heart Failure
52,243 Patients Enrolled for Heart Failure
Retirement Research FoundationOTHER
9 Previous Clinical Trials
1,662 Total Patients Enrolled
Jeanne Maglione, MD, PhDPrincipal InvestigatorUniversity of California, San Diego

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Journal of the American College of CardiologyJournal
Depression in Heart Failure
Rutledge, Thomas, Veronica A. Reis, Sarah E. Linke, Barry H. Greenberg, and Paul J. Mills. 2006. “Depression in Heart Failure”. Journal of the American College of Cardiology. Elsevier BV. doi:10.1016/j.jacc.2006.06.055.
clinicaltrials.govStudy
The Light Heart Study: Daily Light Box Use for Depressive Symptoms in Patients With Stage B Heart Failure
Jeanne Maglione 2015. "The Light Heart Study: Daily Light Box Use for Depressive Symptoms in Patients With Stage B Heart Failure". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02691000.
All > Heart Failure With Preserved Ejection Fraction
~13 spots leftby Apr 2025
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