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LVAD Implant

Active Arm for Heart Failure

N/A
Waitlist Available
Research Sponsored by Abbott Medical Devices
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 3 years post implant
Awards & highlights

Study Summary

This trial looked at whether adding aspirin to a vitamin K antagonist improved outcomes in heart failure patients.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 3 years post implant
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 years post implant for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Non-Inferiority Primary Endpoint
Secondary outcome measures
Rate of Bleeding Rates
Hemorrhage
Rate of Non-surgical Major Thrombotic Events
+3 more
Other outcome measures
Economic Cost Implications
Rate of Rehospitalization
The Hemocompatibility Score (HCS)

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Active ArmActive Control2 Interventions
LVAD Patients on the active arm will be given 100mg Aspirin
Group II: Placebo ArmPlacebo Group2 Interventions
LVAD Patients on the placebo arm will be given placebo medication

Find a Location

Who is running the clinical trial?

Abbott Medical DevicesLead Sponsor
638 Previous Clinical Trials
403,560 Total Patients Enrolled
124 Trials studying Heart Failure
51,068 Patients Enrolled for Heart Failure
Poornima Sood, MD, MBAStudy DirectorClinical Program Director
7 Previous Clinical Trials
4,109 Total Patients Enrolled
6 Trials studying Heart Failure
4,100 Patients Enrolled for Heart Failure

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any available vacancies for participants in this trial?

"As of now, this clinical trial is not accepting new participants. The study was initially published on July 14th 2020 and amended most recently on September 10th 2022. There are currently 701 studies for heart failure and 167 trials investigating Active Arm actively recruiting volunteers."

Answered by AI

What medical conditions is Active Arm often used to treat?

"Active Arm has demonstrated efficacy in treating percutaneous coronary intervention (PCI), dental procedures, and inflammatory conditions."

Answered by AI

At how many locations is this experiment being conducted?

"The clinical trial is being administered at Allegheny General Hospital - ASRI in Pittsburgh, Pennsylvania, Kansas University Medical Center in Kansas City and Mount Sinai Hospital in New york City as well as a further 42 medical centres."

Answered by AI

Could you enumerate the past research projects surrounding Active Arm?

"The Active Arm was first tested fifteen years ago at Clinical Trial Service Unit, NDPH in the University of Oxford. Over five hundred and seventy two trials have been completed to date with a further one hundred and sixty seven actively recruiting; many of these are based around Pittsburgh, Pennsylvania."

Answered by AI

What is the current size of the patient population in this experiment?

"At this time, recruitment for this study has ended. It was first announced on July 14th 2020 and last updated on September 10th 2022. However, those interested in participating in a similar clinical trial can find 701 trials actively seeking patients with heart failure as well as 167 studies related to Active Arm that are still enrolling participants."

Answered by AI

Has this kind of medical trial been conducted before?

"Initially researched in 2005, Active Arm has come a long way since its first trial sponsored by Abbott. After garnering approval during Phase 4 of the study, involving 15480 patients, there are now 167 active trials operating across 1398 cities and 57 countries."

Answered by AI
~132 spots leftby Apr 2025