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Physical Activity intervention arm for Heart Failure

N/A
Waitlist Available
Led By Charles B Eaton, MD, MS
Research Sponsored by Memorial Hospital of Rhode Island
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
alive, community dwelling
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up within 4 years of randomization
Awards & highlights

Study Summary

The WHISH-2-Prevent Heart Failure (HF) study is an ancillary study to the Women's Health Initiative Strong and Healthy (WHISH) exercise pragmatic trial. The WHISH-2-Prevent HF trial examines the intervention effect of physical activity (PA) on both incident HF and HF burden (recurrent HF and CVD death in those with HF) in a cost effective manner in elderly women. In addition, it will allow a dose-finding analysis to better understand the type, intensity and frequency of PA that leads to a reduced risk and burden of HF. The focus of the parent WHISH trial is on atherosclerotic cardiovascular disease and not heart failure.

Eligible Conditions
  • Heart Failure
  • Female
  • Physical Activity
  • Strength Training
  • Aging

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~within 4 years of randomization
This trial's timeline: 3 weeks for screening, Varies for treatment, and within 4 years of randomization for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Heart failure
Secondary outcome measures
Cardiovascular disease mortality
Heart failure with preserved ejection fraction
Heart failure with reduced ejection fraction
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Physical Activity intervention armExperimental Treatment1 Intervention
Receive a tailored behavioral interventions for exercise and strength training via multiple channels including frequent mailings, integrated voice response and outreach phone calls, interactive website, and referral to local community exercise resources.
Group II: Control armActive Control1 Intervention
Receive general health mailings
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Physical Activity
2019
Completed Phase 3
~4710

Find a Location

Who is running the clinical trial?

Wake Forest UniversityOTHER
190 Previous Clinical Trials
114,664 Total Patients Enrolled
5 Trials studying Heart Failure
479 Patients Enrolled for Heart Failure
University at BuffaloOTHER
132 Previous Clinical Trials
49,043 Total Patients Enrolled
National Heart, Lung, and Blood Institute (NHLBI)NIH
3,836 Previous Clinical Trials
47,800,921 Total Patients Enrolled
206 Trials studying Heart Failure
627,512 Patients Enrolled for Heart Failure

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
WHISH-2-Prevent Heart Failure
Charles B. Eaton 2015. "WHISH-2-Prevent Heart Failure". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03099889.
All > Heart Failure With Preserved Ejection Fraction
~4994 spots leftby Apr 2025
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