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Electrolyte Supplement

Magnesium for Obesity

N/A
Waitlist Available
Research Sponsored by Providence VA Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Body mass index greater than 30 kg/m2
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 weeks
Awards & highlights

Study Summary

The objective of this study is to investigate whether nutritional supplementation with magnesium can improve cardiovascular structure and function in participants with obesity - with a long-term goal of preventing clinical heart failure. Specifically, in a randomized open-label pilot study, we will assess whether dietary Magnesium (Mg) supplementation (versus no supplementation) for 24 weeks in obese patients will improve left ventricular (LV) mass.

Eligible Conditions
  • Obesity

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Left ventricular extracellular volume fraction (by cardiac MRI)
Left ventricular mass (by cardiac MRI)
Left ventricular myocardial triglyceride content (by cardiac MRI)
Secondary outcome measures
Aortic pulse wave velocity (by cardiac MRI)
Systolic blood pressure

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: MagnesiumExperimental Treatment1 Intervention
20 participants will be treated with 400 mg of Magnesium Oxide twice daily
Group II: ComparatorActive Control1 Intervention
20 participants will receive no treatment
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
400 mg of Magnesium Oxide twice daily for 24 weeks
2016
N/A
~40

Find a Location

Who is running the clinical trial?

Providence VA Medical CenterLead Sponsor
26 Previous Clinical Trials
72,413 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Magnesium Supplementation for Primary Prevention of Heart Failure in Obesity
Wen-Chih Wu 2016. "Magnesium Supplementation for Primary Prevention of Heart Failure in Obesity". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02966912.
~5 spots leftby May 2025
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