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Heat Therapy Treatment for Heart Disease
N/A
Waitlist Available
Led By Paige C Geiger, Ph.D.
Research Sponsored by University of Kansas Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up cardiac index will be assessed at baseline and 24-48 hours after the last heat therapy session (end of study, ~2.5 weeks after first study visit).
Awards & highlights
Study Summary
This trial will study if heat therapy can improve cardiovascular function by improving the distensibility of the endothelial cells in the arteries.
Eligible Conditions
- Heart Disease
- Cardiovascular Disease
- Endothelial Dysfunction
- Heart Failure
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ systemic vascular resistance will be assessed at baseline and 24-48 hours after the last heat therapy session (end of study, ~2.5 weeks after first study visit).
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~systemic vascular resistance will be assessed at baseline and 24-48 hours after the last heat therapy session (end of study, ~2.5 weeks after first study visit).
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in Blood Pressure
Change in Cardiac Index
Heat shock proteins
+6 moreTrial Design
1Treatment groups
Experimental Treatment
Group I: Heat Therapy TreatmentExperimental Treatment1 Intervention
This study will recruit subjects to participate in heat therapy treatment at the University of Kansas Medical Center (KUMC). After pre-screening, informed consent, and enrollment, all subjects will have baseline hemodynamic assessments as well as VO2max measurements. Subjects will complete 10 heat therapy treatments over the course of 14 days. Hemodynamics will be assessed with the use of the Clearsight© fingertip blood pressure cuff. Within 24-48 hours after the last heat therapy experience, hemodynamic assessments and VO2max will be performed. Blood samples will be collected pre- and post intervention and analyzed for levels of nitric oxide mediators, heat shock protein levels and pro-anti-inflammatory markers.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Heat Therapy Treatment
2019
N/A
~20
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Who is running the clinical trial?
National Institute of General Medical Sciences (NIGMS)NIH
268 Previous Clinical Trials
248,745 Total Patients Enrolled
University of Kansas Medical CenterLead Sponsor
461 Previous Clinical Trials
169,142 Total Patients Enrolled
Paige C Geiger, Ph.D.Principal InvestigatorUniversity of Kansas Medical Center
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