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Pravastatin for Heart Disease

N/A
Waitlist Available
Research Sponsored by National Center for Research Resources (NCRR)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
No history of hypertension
No history of coronary artery disease
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial will examine if pravastatin, an HMG-CoA reductase inhibitor, improves blood vessel functioning after a fatty meal.

Who is the study for?
This trial is for healthy individuals aged 18-40 without diabetes, high blood pressure, smoking habits, or heart disease. It's designed to see if pravastatin can prevent blood vessel issues after eating a fatty meal.Check my eligibility
What is being tested?
The study tests whether pravastatin improves how blood vessels function following a high-fat meal. Participants will be randomly given either pravastatin or a placebo for four days and then switch groups.See study design
What are the potential side effects?
Pravastatin may cause side effects like muscle pain, nausea, headache, and dizziness. However, it's generally considered safe with minimal side effects in most people.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have never been diagnosed with high blood pressure.
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I have never had heart artery disease.
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I have never been diagnosed with diabetes.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

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Who is running the clinical trial?

National Center for Research Resources (NCRR)Lead Sponsor
537 Previous Clinical Trials
317,016 Total Patients Enrolled

Media Library

Placebo Clinical Trial Eligibility Overview. Trial Name: NCT00005117 — N/A
Heart Disease Research Study Groups:
Heart Disease Clinical Trial 2023: Placebo Highlights & Side Effects. Trial Name: NCT00005117 — N/A
Placebo 2023 Treatment Timeline for Medical Study. Trial Name: NCT00005117 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is eligibility for this trial restricted to those younger than 65?

"Eligibility for this clinical trial stipulates that potential participants must be younger than 40 years old and at least 18."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Effect of Pravastatin on Endothelial Dysfunction Following a Single High Fat Meal
2024. "Effect of Pravastatin on Endothelial Dysfunction Following a Single High Fat Meal". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00005117.
All > Heart Disease
~233 spots leftby Apr 2025
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